The role of vitamin D in auto-immune conditions and especially MS has been studied for decades. It is a proven epidemiological fact that MS rates steadily increase with latitude (low sunlight exposure) and are virtually nil in people living in tropical or equatorial areas of the globe. Despite this proven relationship, medicine refuses to consider vitamin D as a prophylactic or treatment intervention for MS. The study below demonstrated that a relatively low, human-equivalent dose of 20,000 IU – 25,000 IU of vitamin D3 once weekly for just 6-7 weeks was able to not only ameliorate the symptoms of advanced MS, but it actually showed a trend towards a reversal of the condition.
https://pubmed.ncbi.nlm.nih.gov/37571246/
https://nutraceuticalbusinessreview.com/vitamin-D-multiple-sclerosis-late-stage
“…Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) that affects around 13,500 people in Austria. Due to the different ways it progresses and its variety of symptoms, the “disease with a thousand faces” is difficult to research and treat. In a study conducted by the neuroimmunology research team at the Department of Neurology, Michaela Tanja Haindl has investigated in a laboratory model how vitamin D has an effect in late-stage multiple sclerosis and what consequences this may have for MS research in general.”
“…It was demonstrated that significantly more cellular structures were preserved in this part of the brain in rats given vitamin D in addition to their normal diet. Not only were myelin and nerve cells better preserved, but there was also a reduction in apoptotic cells and microglial activation. Animals given vitamin D had significantly fewer serum neurofilament light chains (sNfL). These filaments are currently regarded as a predictor of nerve cell damage and thus a biomarker for the progression/severity of multiple sclerosis. In addition, the vitamin displayed an antioxidant effect in test animals, which was also detected in the blood serum. Rats treated with vitamin D had not only significantly more protective polyphenols in their blood, but a higher total antioxidative capacity (TAC) as well. Since oxidative stress is considered to possibly trigger and intensify MS, this positive effect of the “sunshine vitamin” might be substantiated by further research.”
