Lactate is a key driver of diabetes/obesity, by promoting inflammation

A great study, demonstrating that in diabetes (just as in cancer) the so-called Warburg Effect (aerobic glycolysis) is as much a cause of those degenerative conditions as it is an effect of. The study below demonstrated that increased intracellular lactate results in robust increase in systemic release of inflammatory cytokines, resulting in aggravation of systemic … Read more

Exercise brain-boost may be due simply to increasing brain selenium levels

Yet another study demonstrating that many of the “mysterious” benefits of exercise most likely have nothing to do with the (insignificant) amount of extra calories burned, but are due to peripheral effects related to metabolism and redox balance. Namely, the study below investigates the well-known phenomenon that neurogenesis (which declines strongly with age) is strongly … Read more

“Reductive” stress harms cells, mitochondria protect by increasing metabolism

Finally a study that provide me with some “ammo” during my arguments with people I know who work in the medical profession. A common topic in such arguments is the mainstream medical idea that it is almost impossible to have too much antioxidants and too little oxidation. In fact, to many doctors it is excessive … Read more

High blood PUFA “a specific feature of severe COVID-19 pneumonia”

The evidence for PUFA being a crucial pathological factor in yet another disease is probably not surprising to my readers. The reason I like this study is that since COVID-19 is still (unfortunately) the main topic of the day in most Western countries, a study discussing PUFA in a COVID-19 context may get a lot … Read more

Not a “male” hormone – testosterone (T) beneficial for female heart health

It always feels good to read an article on a scientific discovery and have one of the authors put on his Peat-y hat and quote Peat directly. I am joking, of course, but the study below and the statements from its lead author do sound like Peat had a significant participation in the study write-up, … Read more