Blocking cortisol may treat terminal pancreatic cancer

Recently, I made a post about some truly amazing results in treating terminal cancer patients with the glucocorticoid/progesterone antagonist Mifepristone (RU486). Some of the cases were stage 4 and possibly terminal. Now, a new case study below reports possibly curative effects on a confirmed terminal case of pancreatic cancer using 200mg daily dose of RU486. … Read more

Replacing starch with sucrose increases metabolism, prevent obesity

A study that will certainly generate controversy in the low-carb blogosphere, but the findings are hard to dispute. Namely, feeding a diet for 15 weeks, in which 74.3% of the calories come from carbs in the form of starch was clearly obesogenic, caused insulin resistance and elevated blood glucose, triglycerides, and free fatty acids (FFA). … Read more

Vitamin D can force cancer cells to differentiate back into normal

Danny and I already discussed this topic on a recent podcast, but I decided to post the studies anyways, considering how important the topic is. While progesterone and testosterone are the most well-known differentiating factors in humans, the role of vitamin D has gone largely unnoticed. The studies below demonstrate that vitamin D is a … Read more

Oral testosterone + vitamin E may treat NAFLD, NASH, cirrhosis in humans

Several years ago, I posted a few studies from the 1970s demonstrating very high cure rates of advanced cirrhosis in humans with a combination treatment of testosterone (T) and vitamin B1 (thiamine). Not bad for a condition modern medicine tells us is incurable and the only option the patient has is a liver transplant. … Read more

Androgens (T, DHT) highly protective against the flu

A gem of a study that throws a wrench in one of medicine’s core dogmas – i.e. androgens have detrimental effects on the immune system and males have evolved to live with a trade-off between high androgen levels (and as such high fertility) and higher risk of severe viral episodes that can be even deadly. … Read more

Stress (cortisol) causes pre-term birth by blocking progesterone

If you ask a gynecologist what causes premature birth, the answer will usually be something along the lines of “insufficient progesterone” often accompanied by mumbling about “genetic predispositions”. Yet, how exactly is insufficient progesterone responsible for premature birth has remained a mystery, at least for most practicing doctors. Back in the first half of the … Read more

Metabolic (energy) deficiency may be the cause of Parkinson Disease (PD)

The dogma that PD is just a simple dopamine deficiency manifesting in genetically vulnerable individuals is quickly becoming untenable. It is well-known among clinicians that administering dopamine precursors such as L-Dopa, or selective dopamine agonists such as pramipexole has limited therapeutic effects for PD patients and invariably become ineffective after a few years of use. … Read more

Aspirin may prevent and treat COVID-19

I may get banned from social media for making a post with such a title, but I am simply reporting on what the study discovered. Namely, even a low-dose aspirin used mostly for ischemic attack (heart or brain) prevention reduced risks of SARS-CoV-2 infection by almost 30%, while also shortening the duration of infection by … Read more

Serotonin (5-HT) is a key driver of asthma

Yet another blow to the status of the so-called “happiness hormone”. While histamine, acetylcholine, and estrogen have long been known as key drivers of asthma the link between the mast cells and the nervous system’s production of the vasoconstrictor acetylcholine has remained unknown. The study below demonstrates that the release of serotonin (5-HT) from mast … Read more

PUFA metabolites may drive bacterial infections and their resistance to antibiotics

The study below demonstrates yet again that there is hardly an aspect of human health that PUFA does not influence in a detrimental manner, even seemingly non-metabolic aspects such as bacterial infections. As it turns out, most bacteria express the enzyme family known as lipoxygenases (LOX) and uses those enzymes to evade the endogenous immune … Read more