Category: Science

Scientific articles and discussions, with my comments and take on the topics therein.

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Inosine directly binds and blocks the endotoxin/LPS receptor (TLR4)

Inosine is an endogenous purine and a breakdown product of ATP. Elevated inosine levels are observed in…

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Elevated cortisol/DHEA-S ratio (a sign of chronic stress or low metabolism) may drive Alzheimer Disease (AD)

As my readers know, from both Ray work and mine, cortisol has a proven detrimental role in…

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Elevated extracellular serotonin (5-HT), not dopamine, drives compulsive sexual behavior (CSBD)

Yet another study showing that mainstream medicine’s claims about the origins of a mental health condition are…

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Keto diets may drop some weight, but cause hyperlipidemia, liver/heart disease, and even diabetes type I

This is probably one of the most controversial posts I have made in a long time. It…

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Wasting syndrome (cachexia) driven by low metabolism/NAD+; can be blocked/reversed

One of those articles that fully corroborates Ray’s views that metabolism is central not only to “function”,…

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Age-related inflammation driven by declining mitochondrial function; menopause likely reversible

Yet another study demonstrating the key role metabolism plays in aspects of health firmly considered by medicine…

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Endotoxin/LPS, even in tiny amounts, is the most inflammatory component of air pollution

Several years ago, I did a post on a study that looked at the COVID pandemic measures…

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Endotoxin/LPS is a major driver of blood clotting, sepsis, heart attacks and strokes

The issue of blood clotting and what exactly triggers it (even in healthy people) remains a “mystery”…

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Low-carb diet and chronic (even mild) stress sufficient to cause heart disease (CVD) and depression

I first tried low-carbing, circa 2008, and quickly realized just how detrimental it is to health, especially…

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A reductive state (high GSH, NAC, NADH/NAD+ ratio, etc), activates the cortisol/estrogen pathways; oxidizing/ pro-metabolic agents block them

Ray mentioned in a few of his articles that a reductive state, characterized by a buildup of…