Recent Posts
Glycine (or serine) deficiency drives pancreatic cancer, at least in part by increasing fatty acid oxidation
About a decade ago, a very controversial study came out, which claimed to demonstrate that the amino…
Even a brief exposure to high-fat diet is inflammatory, low-fat diet is not; diet, not BMI, drives pathology
A study that is bound to further exacerbate the “controversy” of high-fat diets (HFD) vs. low-fat diets…
Vitamin D reverses (skin) aging and extends lifespan
One of the lesser known effects of vitamin D is that it activates the so-called longevity gene…
PUFA metabolites (leukotrienes) drive scar tissue growth, blockade is therapeutic
Once again, PUFA rears its ugly head in health areas traditionally considered not related to fat metabolism…
By lowering dopamine, serotonin (5-HT) reduces metabolism, physical activity, endurance; promotes fat gain/oxidation
One of the rare studies that truly shines the light on just how systemically nefarious 5-HT is….
L-carnitine synergizes with endotoxin/LPS to drive systemic inflammation and muscle injury
Just a few weeks ago, I did a post on the anti-acid drug famotidine being a potent…
PUFA peroxidation byproduct and endotoxin/LPS drive ALS and are reliable predictors of its lethality
Yet another lethal condition, for which no known treatment exists or is even in the pharma drug…
An estrogen-family receptor (ERRy) drives cancerization, age-related strength decline; blocking ERRy reverses at least the latter
The reintroduction of estrogen hormonal therapy (HRT) may go down in history as one of the biggest…
Cholesterol is a cellular “lifesaver”; inhibiting its synthesis (e.g. statins) poisons cells through mitochondrial debris and fatty acids
Despite the mountain of evidence that messing with cholesterol is a bad idea, especially when it comes…
Omega-3 (fish oil) is toxic to the brain and inhibits recovery after traumatic injury (TBI), may cause Alzheimer’s
One of the few studies that is willing to call a spade a spade. Despite the lack…