Maternal high-PUFA diet causes alcoholism, aggressiveness, early puberty, and hyper-estrogenism in offspring

Finally, an intervention study that should help convince some of the die-hard PUFA fans that these fatty acids are far from benign/beneficial, but in fact can cause a variety of chronic diseases. A very important finding of the study, that distinguishes it from other PUFA studies, is that it demonstrates without a doubt the estrogenicity … Read more

Stress ups cortisol/estrogen/prolactin, drops DHT, causes male infertility and prostate issues

If you try to discuss infertility with a fertility/reproductive specialist or an endocrinologist, and mention that chronic stress may be a factor in infertility, you will probably get laughed out of the room. This is not just speculation. This exact same thing happened to several friends and relatives who struggled to conceive, and it is … Read more

Cortisol causes fatty liver (as well as obesity, diabetes, etc)

Not really a surprise for most of my readers, but it is always nice to see more evidence establishing various disorders attributed to “gluttony”, “weak will”, “addiction”, etc as actual endocrine disturbances. And since the current study implicates cortisol, we can point the finger once again at (chronic) stress. While the current study mostly focused … Read more

COVID-19 is an energy deficiency disease

Yet another seemingly non-metabolic disease turns out to be nothing but energy deficiency in disguise. Apparently, the SARS-CoV-2 virus selectively disables so-called complex I of the electron transport chain (ETC), and as such the overall OXPHOS process. Such inhibition is known to reliably increase the production of reactive oxygen species (ROS), which is known to … Read more

Hyperserotonemia confirmed as a cause of autism and insomnia

Given the flood of recent studies lately, with virtually identical findings as the study below, I don’t think much needs to be said. So much for “serotonin is the happiness hormone”…Yet despite the solid evidence implicating serotonin as a (if not THE) major cause of autism, even this study did not dare mention blocking serotonin … Read more

Loss of mitochondrial function (OXPHOS) induces de-differentiation

The study only focuses on the lymphatic system and its cells, but the principle is general and has been observed in other organ/tissue cells. The most obvious example is cancer – no matter which organ it occurs in, the tumor is composed of de-differentiated cells not unlike the stem cells from which all other tissues/organs … Read more

High PTH, low vitamin D implicated in bipolar disorder (BD)

A great study highlighting once again the importance of calcium, vitamin D and especially the pro-inflammatory parathyroid hormone (PTH) for mental health. While there are many studies (both observational and intervention ones) examining the role of vitamin D in mental health, this is one of the very few looking into the role of PTH. It … Read more

Working too hard / long can kill you

Another study directly implicating work stress in not only chronic, degenerative conditions but also death directly. Apparently, as corrupt/inept as W.H.O is, the evidence linking hard work with early death is too strong even for them to ignore. Btw, what the study used as definition for “hard” and/or “long” work would come as a surprise … Read more

Mitochondrial dysfunction may be the cause of anemia

Despite anemia being a pretty common condition, I still don’t think medicine has a good idea what causes anemia (putting aside the more obvious reasons such as chronic bleeding and dietary iron deficiency). In one of the KMUD interviews Peat opined that in his opinion true¬† iron deficiency anemias were rare and the anemias characterized … Read more

Muscle weakness / wasting linked to poor mitochondrial function

A study that once again illustrates the central principle of bioenergetics – structure and function cannot be separated. They are interdependent at every level. In this specific case, the “structural” pathology is muscle weakness and wasting (sarcopenia, cachexia, etc). Most doctors, when evaluating such condition, will look for structural problems such as genetic mutations, trauma, … Read more