Levothyroxine (T4) monotherapy often ineffective for hypothyroidism

As most of my readers know, the currently approved therapy for hypothyroidism is levothyroxine (T4). While technically T3 and combined T4/T3 therapy are also approved by FDA, the former is only used in severe cases of myxedema and the latter is considered obsolete and a remnant of the days when the use of natural dessicated … Read more Levothyroxine (T4) monotherapy often ineffective for hypothyroidism

Long Work Hours Linked to Hypothyroidism

The connection between stress and health issues is perhaps the best kept “public secret”. As the saying goes, the only people who do not believe in the pathology of stress are doctors…and the dead. I would add to this category the profession of statisticians who publish studies like the one below. Despite demonstrating “dose-dependent” relationship … Read more Long Work Hours Linked to Hypothyroidism

Restoring glucose metabolism may treat Crohn’s disease (CD)

As my readers know, the role of metabolism in the initiation and progression of cancer is enjoying renewed interest, after more than a century of neglect and deliberate suppression. One of the promising drugs that target metabolic pathways is dichloroacetate (DCA). The main mechanism of action for DCA is its ability to restore glucose oxidation … Read more Restoring glucose metabolism may treat Crohn’s disease (CD)

Pregnenolone (P5) – a new osteoporosis drug

About a month ago, I made a post in regards to aspirin becoming a new treatment for osteoporosis. Several months ago, I made another post about an in-vitro study demonstrating powerful anabolic effects of pregnenolone (P5) on bones. Apparently, the protective effects of P5 on bone health are known in certain circles and there have … Read more Pregnenolone (P5) – a new osteoporosis drug

PUFA are toxic/carcinogenic, and that has been known for decades

Quite a statement in that title but apparently that is what the current state of knowledge is, if one cares to dig a bit under the surface of lies/deception spread by public health authorities and even primary care doctors. Apparently, in some circles, the effect of PUFA on the human brain is known to rival … Read more PUFA are toxic/carcinogenic, and that has been known for decades

Striking accumulation of PUFA in aged cells

Peat has written many times about the changes that occur in “aged” cells. Those changes are virtually indistinguishable from the ones that occur in “sick” cells and are characterized by reduced mitochondrial number/size and a shift in lipid composition away from saturated and towards unsaturated fats. The crucial mitochondrial lipid enzyme cardiolipin (CL) comprises at … Read more Striking accumulation of PUFA in aged cells

PUFA may be a major factor in sterility

Just a few days ago I made a post about PUFA driving obesity, inflammation, and liver damage in diabetes II patients. The omega-6 fatty acid DLGA (a metabolite of linoleic acid) was the main pathological factor examined in that study. Now, a new study study demonstrates that DLGA may also cause sterility. Official estimates indicate … Read more PUFA may be a major factor in sterility

PUFA increases risk of all cancers, especially prostate

The bad news for PUFA just keep on coming. There seems to be no health pathology that PUFA does not promote, even indirectly. The study below demonstrates that BOTH omega-3 and omega-6 increase risk of ANY cancer and death from it, but specifically the risk of aggressive prostate cancer. It is mind boggling that in … Read more PUFA increases risk of all cancers, especially prostate

Diet (PUFA) causes inflammatory bowel disease (IBD)

Rates of inflammatory bowel diseases (IBD) such as ulcerative colitis (UC) have been steadily increasing and predominantly so in the youngest cohorts studied. The official cause of UC is of course “unknown” even though the public health authorities do admit that an environmental agent is most likely at fault. UC is an “autoimmune” condition and … Read more Diet (PUFA) causes inflammatory bowel disease (IBD)