Both “long” COVID-19 and CFS are likely caused by hypometabolism

A good study that examines the remarkable parallels between the so-called “long” COVID-19 (i.e. chronic display of symptoms associated with COVID-19) and the (in)famous chronic fatigue syndrome (CFS). Namely, increases inflammation, excessive glycolysis, suppressed mitochondrial function and decreased synthesis of ATP. Despite all of these known signs of both pathologies, no study so-far (including the … Read more

Manufactured citric acid is a powerful inflammatory/allergy agent

I great study, which goes hand-in-hand with another one I recently posted about in regards to silica (ubiquitous in commercially sold food products/drinks). Namely, just as that other study found silica to be a potent inducer of the endotoxin/LPS receptor TLR4 even in minute amounts, this study below describes the powerful inflammatory effects of manufactured/citric … Read more

Aspirin reduces symptom severity, COVID-19 mortality by half

Another great result for aspirin, which I suspect will not see much mainstream media publicity and will probably get censored the moment it hits my Twitter feed:-) Be that as it may, at this point the evidence for available successful/effective treatments for COVID-19 becomes too big to ignore, which of course invalidates the legal rationale … Read more

Blocking the endotoxin receptor (TLR4) may prevent / treat hearing loss

I did a post a few months ago on the connection between tinnitus and serotonin – i.e. using anti-serotonin drugs may treat tinnitus. Since tinnitus is almost always a precursor state to hearing loss (and eventually deafness), the two conditions obviously go hand-in-hand and are likely caused by the same agent (e.g. serotonin). Since more … Read more

Air pollution impairs cognition, aspirin is protective

A new study demonstrating that even short-term (less than a month) exposure to polluted air impaired cognition in humans, and that the mechanism of action was by triggering an inflammatory response. Ergo, anti-inflammatory drugs (NSAID) and especially aspirin, were found to be protective. Since the anti-inflammatory effects of aspirin focus mostly on the COX family … Read more

Inflammation (from PUFA), not telomeres, determines lifespan / healthspan

The idea of lifespan being entirely determined by limits on cellular division has ruled biology for more than a century and is perhaps best exemplified by the (in)famous (and false) Hayflick limit. Reaching the said limit is postulated to be controlled by telomere length, and as such the simplistic hypothesis materialized that could extend/control lifespan … Read more

Endotoxin (LPS) may be the cause of fatal lung damage in COVID-19

Yet another study, which demonstrates that there is virtually no disease (acute of chronic, infections or not) where the infamous LPS does not play a causative role. As it turns out, the often fatal inflammatory reaction (cytokine storm) that usually kills patients with COVID-19 in ICU, is driven by endotoxin through activation of its TLR4 … Read more

Aspirin beneficial, other NSAID harmful, for COVID-19

Once again, the miracle of nature known as aspirin gets some recognition. Studies done early in the COVID-19 pandemic (early 2020) suggested that non-steroid anti-inflammatory drugs (NSAID) may help reduce severity/lethality of COVID-19, however subsequent studies challenged those results and demonstrated worse outcomes in patients treated with NSAID. As more and more studies were done … Read more

Silica, present in most supplements/food, activates the endotoxin receptor (TLR4)

Many of my readers know about the health risks of silica – a substance doctors and pundits call completely “benign, present in virtually all commercially sold dietary supplements and also in most commercially sold food (even organic ones!). The most commonly used form commercially is silicon dioxide, which is essentially powdered glass! However, despite its … Read more

Androgens (T, DHT) highly protective against the flu

A gem of a study that throws a wrench in one of medicine’s core dogmas – i.e. androgens have detrimental effects on the immune system and males have evolved to live with a trade-off between high androgen levels (and as such high fertility) and higher risk of severe viral episodes that can be even deadly. … Read more