Mitochondrial debris (from stress/injury) causes “autoimmune” disease

After dancing around the issue for the last 10+ years, it looks like medicine is finally ready to admit the obvious. Namely, cellular (and more specifically, mitochondrial) debris created by stress/injury and dumped into the bloodstream causes the (in)famous “flares” that define virtually all “autoimmune” conditions and are the main focus of doctors and pharma … Read more

Vitamin D effective in humans for preventing autoimmune diseases

A human study, one of the largest ever conducted, and covering virtually all major autoimmune conditions. Also, the study claims that this is the first intervention trial that looked at effects of vitamin D on developing autoimmune conditions, so the link is causal – i.e. we can now claim that taking vitamin D does prevent … Read more

Blocking PUFA metabolism therapeutic for Multiple Sclerosis (MS)

The rates of MS have been steadily rising over the last several decades. While mainstream medicine claims the cause is “unknown”, it is well known that it has an almost perfect inverse association with sunshine exposure, vitamin D levels, aspirin usage, histamine blockers, etc. This suggest an inflammatory cause, which implicates PUFA since the majority … Read more

Serotonin, SSRI drugs may be the cause of IBD, Parkinson’s, diabetes, etc.

A great new study that points the finger straight at serotonin (5-HT). It has been known since the 1940s that not only is 5-HT produced predominantly in the GI tract, but also that elevated serotonin levels are causally linked to a plethora of chronic conditions, especially various inflammatory bowel diseases (IBD) such as Crohn’s, ulcerative … Read more

Endotoxin (LPS) causes rheumatoid arthritis…and COVID-19

A great new study, which is perhaps the first to directly point the finger at endotoxin as perhaps the main cause of rheumatoid arthritis (RA). RA is an “autoimmune” condition and not only shares symptoms with other similar conditions such as Lupus, psoriasis, MS, etc, but now all of them are considered officially to be … Read more

Mitochondrial debris leaking in bloodstream may cause autoimmune disease

This has been a recurring topic in my posts, and I am glad to see that more and more scientists are starting to take seriously the idea that chronic stress may be the ultimate cause of most/all “autoimmune” conditions. The whole idea of the immune system suddenly starting to attack an organ/tissue is quite bizarre … Read more

Estrogen can both cause and exacerbate Lupus

A quick post as a response to a recent argument I had over email with an endocrinologist who follows me on Twitter. His claim was that the causes of Lupus are currently unknown but are likely “multifactorial” and me ascribing such causes to “isolated peculiarities” such as endotoxin (LPS) or estrogen is unwarranted. The fact … Read more

Stress (cortisol) can cause ANY autoimmune condition by disrupting gut barrier

A great new study that is not afraid to point out the paradox between mainstream medicine’s claims of beneficial effects of cortisol and the reality of “autoimmune” conditions more often than not being associated with elevated levels of CRH, ACTH and cortisol. The role of CRH as a causative factor in a number of chronic … Read more