Vitamin D Deficiency Can Lead to Dementia And Stroke

Despite this being an observational study, the analysis for extraneous factors has been strong enough that the authors believe the link between vitamin D deficiency and dementia/stroke is causal. As the study itself says, almost 20% of dementia/stroke cases could be prevented by simply supplementing with vitamin D. And since by supplementation such studies often … Read more

Ocular progesterone administration may treat eye, brain, and mental illness

A few months ago, I posted a study demonstrating improvement in localized, ocular steroidogenesis by administration of a small amount of niacinamide (as an aqueous solution) directly into the eye. It looks like ocular administration of a variety of substances is a hot topic in research circles, as I saw a number of other studies … Read more

Allopregnanolone found safe, may slow brain atrophy from Alzheimer’s

A great new study, which is one of the very few to examine the safety and effectiveness of allopregnanolone in humans. The trial was conducted in patients with Alzheimer Disease (AD) and aimed to establish the safety of various doses of once-weekly allopregnanolone administration, as well as any potential benefits on brain morphology in AD … Read more

Blocking endotoxin may reverse cognitive decline of aging

Another study implicating endotoxin (LPS) and its associated receptor (TLR4) in a phenotype of aging considered “normal” by mainstream medicine, though it almost universally progresses into dementia territory with advancing age, to the point where 90%+ of people over 85 have at least moderate levels of dementia, even if not officially diagnosed with Alzheimer’s disease … Read more

Exercise brain-boost may be due simply to increasing brain selenium levels

Yet another study demonstrating that many of the “mysterious” benefits of exercise most likely have nothing to do with the (insignificant) amount of extra calories burned, but are due to peripheral effects related to metabolism and redox balance. Namely, the study below investigates the well-known phenomenon that neurogenesis (which declines strongly with age) is strongly … Read more

Cellular “memory” of stress can be passed on for 50+ generations

There was a study that came out 2-3 years ago showing that when animals were exposed to a toxin, often the negative effects did not even manifest in the directly exposed organism but manifested in their offspring and were passed on for more than 14 generations. The study below now demonstrates that the effects of … Read more

Hyperserotonemia confirmed as a cause of autism and insomnia

Given the flood of recent studies lately, with virtually identical findings as the study below, I don’t think much needs to be said. So much for “serotonin is the happiness hormone”…Yet despite the solid evidence implicating serotonin as a (if not THE) major cause of autism, even this study did not dare mention blocking serotonin … Read more

DHT, not T, likely the “active” androgen in heart and brain

Interesting study, done on baboons (so should have good relevance for humans), demonstrating that the cardiovascular system (CVS) exclusively accumulates and recognizes (at the receptor level) DHT, instead of testosterone (T). In fact, the androgen receptor in CVS is so structurally different it apparently cannot even bind T. Recent studies with ALS patients suggest the … Read more

Childhood stress causes mental illness in adults by blunting androgens

Yet another great study solidifying the evidence on just how detrimental early childhood stress is. It has been known for decades that childhood stress leads to early puberty, and that the latter is associated with greatly increased risk of chronic diseases later in life, as well as early death. However, mainstream medicine has always heatedly … Read more

Blocking PUFA/prostaglandins restores metabolism and reverses brain aging

The bad news for PUFA has been accumulating for decades, yet public health authorities continue to claim that type of fat is “essential”. Whatever indirect admissions of the pathological role of PUFA in both chronic and acute/infectious diseases is given to the public, is usually confined to the well-known PUFA metabolites known as prostaglandins. However, … Read more