Another study that contradicts the pervasive dogma that higher T levels are a nightmare for aging males, leading to everything from baldness, to prostate cancer, to heart disease, and even diabetes. Speaking of diabetes, the study found the exact opposite – i.e. the higher total T levels were in a male under 65, the lower his risk of developing diabetes was. Unfortunately, our modern lifestyle of bathing in endocrine disruptors 24×7 decimates male T levels, and so do a number of very widely prescribed pharma drugs (statins, PPI inhibitors, blood-thinners, etc). Be that as it may, it would be nice to see a subsequent study examine the role of cortisol as well, since a few studies with longer term measurements (done in hair or nails) of cortisol (F) and testosterone demonstrated positive associations of F, but especially of the F/T ratio with obesity, diabetes, and CVD, thus implicating directly chronic stress in this metabolic/endocrine condition.
https://www.endocrine.org/news-and-advocacy/news-room/2024/endo-2024-press-umapathysivam
“…A new study says higher levels of testosterone can lower the risk of type 2 diabetes for men 65 years or younger who are overweight or have obesity. The study, which hasn’t been published yet in a peer-reviewed journal, was presented today at ENDO 2024, the Endocrine Society’s annual meeting in Boston. Mahesh Umapathysivam, a lead researcher from the University of Adelaide in Australia, said in a statement that the research team wanted to better understand the relationship between testosterone and type 2 diabetes risk across a range of testosterone levels. He said they also wanted to examine interactions between testosterone and different diabetes risk factors in midlife and in older men. “A low blood testosterone concentration is an independent risk factor for developing type 2 diabetes, and high levels of testosterone appear protective against the development of type 2 diabetes,” Umapathysivam said. The team examined data from the MAILES Cohort, a group of men ages 35 to 85 years living in urban Adelaide.”
