Glucose + vitamin B3 combo synergistic for treating mitochondrial disease

A very interesting study, which demonstrates the unique synergy between glucose and vitamin B3 in treating deficiencies of function in Complex I & II of the electron transport chain (ETC). Deficiencies on those metabolic steps are the most common causes for the wide varieties of debilitating symptoms (or even death) in people with “inborn” mitochondrial … Read more

Niacinamide as treatment for scleroderma (systemic sclerosis)

Yet another “incurable” disease has been demonstrated to be nothing more but energetic deficiency in disguise. According to mainstream medicine, scleroderma (also known as systemic sclerosis) is an incurable chronic, autoimmune, progressive, fibrotic disease that attacks virtually all organs and can lead to significant disability and even death if it affects some of the more … Read more

Glaucoma likely a metabolic disease, treatable by pyruvate and/or niacinamide

About a year ago, a publication came out that demonstrated therapeutic effects of raising the (mitochondrial) NAD/NADH ratio in glaucoma patients. That study used niacinamide (NAM) and suggested that the “irreversible” changes in eye structure seen in glaucoma patients are in fact nothing more than a downstream effect of metabolic (OXPHOS) disturbances. Now, a new … Read more

Niacinamide may treat ALS by improving energetic state

Another study sent to me by the Austrian collaborator. Once again, the energetic origin of “incurable” diseases like amyotrophic lateral sclerosis (ALS) is on full display. The study elucidates that ALL types of ALS are characterized by metabolic/energetic abnormalities and the metabolic phenotype of that disease is indistinguishable from cancer. In other words, little to … Read more

Vitamin B3 may treat “incurable” muscle disease

Over the last 2-3 years I have seen a dramatic increase in the number of studies and popular press articles using the keywords “controversial”, “paradox”, “paradigm shift”, “ameliorates an incurable condition X”, etc. This is just a thinly veiled attempt to mask the collapse of the corrupt dogma that has controlled medicine for more than … Read more

Raising NAD levels may be therapeutic for COVID-19

A rather timely study, which demonstrates once again the crucial role energy plays even in “non-metabolic” diseases such as viral infections. At this point, even mainstream medicine admits that every function of the organism requires energy, so it would be plausible to expect an organism with higher energy reserves to be better able to defend … Read more

Vitamin B3 remarkably therapeutic for brain cancer (glioblastoma)

As many of my readers know, brain cancer rates have been steadily rising over the last 3 decades and are now a leading cause of death in both elderly and also very young people. The most common (and deadly) form of brain cancer is glioblastoma multiforme and the average life expectancy after diagnosis is just … Read more

Niacinamide may treat fibrotic eye disease and prevent vision loss

A great new study that demonstrated nicotinamide (NAM) may also have anti-fibrotic effects in addition to its positive effects on maintaining favorable NAD/NADH ratio and redox balance. The mechanism of action of NAM was inhibition of the TGF-β pathway and overall reduction of inflammation. This anti-fibrotic effect of NAM may explain its well-known protective effects … Read more

Forcing the heart to burn glucose instead of fat may cure heart failure

One of the blockbuster studies I have seen over the last 12 months. It reads as if written by Peat himself and discusses tissue regeneration, Randle cycle, dietary control of metabolism, etc. AFAIK this is the first study brave enough to demonstrate that simply switching fuel types in an organism can have profound structural effects, … Read more