Tag: OXPHOS
Increasing the metabolic rate increases lifespan and improves health
The study below is one of the few to directly challenge the so-called Rate of Living Theory…
Niacinamide improves bone health and reduces fat synthesis
Two of the features of aging thought to be unavoidable are brittle bones and increased visceral fat,…
Brain energy production determines our psychosocial experience; stress damages it
Well, it does not get any clearer than the findings of the study below. Namely, the old…
Lactate damages mitochondria and can cause (pulmonary) fibrosis
In the first half of the 20th century lactate had a largely negative reputation in medical circles…
PUFA can cause male infertility by inhibiting oxidative metabolism (OXPHOS)
The study looked at one of the members of the PUFA family that even mainstream medicine is…
Childhood stress causes muscle dysfunction in adulthood by damaging oxidative metabolism
Yet another study demonstrating that many mysterious, and sometimes severe/fatal (e.g. ALS) muscle-related conditions may be not…
Estrogen and cortisol inhibit mitochondrial oxidation, vitamin E reverses the inhibition
More specifically, those steroids inhibit NADH (also known as DPNH) oxidation in the mitochondria, which shifts the…
The pro-metabolic drug DNP, banned by FDA, may treat most diseases
The chemical 2,4-dinitrophenol (DNP) is one of the oldest (and most successful) weight loss drugs. It works…
An estrogen metabolite may drive pulmonary arterial hypertension (PAH)
Just a few minutes ago I did a post on the causative role of estrogen and its…
Immunodeficiency driven by mitochondrial dysfunction, can be reversed
This is study that has very wide applicability since the immune system plays a role not only…