Fasting causes aging by energy depletion, vitamin B2 can stop it

Well, if this title does not rile up the fasting crowd, I don’t know what will:-) Aside from that controversy, it is actually a great study that not only suggests a dirt cheap and widely available option for retarding aging, but once again demonstrates that stress (e.g. fasting) directly causes aging by depleting/blocking OXPHOS, and … Read more

Fasting / stress decimate gonadal steroidogenesis, with no effect on blood cortisol

A very interesting and very “controversial” (read: inconvenient truth) study, since it shows beyond reasonable doubt that even brief (4 days) fasting is a form of severe stress, at least when it comes to endocrine health. The study may also provide answers to various endocrine “mysteries” becoming more common among the male population of “developed” … Read more

Scoliosis (even in females) may be driven by low androgen levels, DHT may treat it

I am posting about this condition as it seems recently its numbers have absolutely exploded in the general population. Scoliosis used to be a relatively uncommon condition, usually present in adults over the age of 50. Mainstream medicine has no explanation for its possible causes, but suspects inflammation is involved. The study below suggests that … Read more

Vitamin D3 anabolic, calcitriol catabolic for muscle/thymus

Several great studies, which will probably do little to calm down the controversy that seems to be brewing lately in the blogosphere over whether supplementing with vitamin D3 is beneficial or not. Namely, the last study below demonstrated direct muscle-anabolic effects from supplementation with vitamin D3 (cholecalciferol), in direct opposition to the known catabolic effects … Read more

Exercise causes (and worsens) arterial calcification

A great new study sent to me by one of my blog’s readers. It will more than likely cause a lot of controversy, despite its findings having a very simple explanation. Namely, chronic exercise increases baseline cortisol and over time, cortisol (acting through the aldosterone/mineralocorticoid receptor) causes vascular calcification. High aldosterone, caused by chronic salt … Read more

Serotonin puts the brakes on libido, by lowering dopamine

Nothing really surprising, as far as Peatarians are concerned, in the findings of this study. I am only posting it here as it is one of the few that officially acknowledge that serotonergic drugs cause sexual dysfunction – i.e. something mainstream medicine has vehemently denied for decades. As such, it corroborates the approach of using … Read more

Cellular “memory” of stress can be passed on for 50+ generations

There was a study that came out 2-3 years ago showing that when animals were exposed to a toxin, often the negative effects did not even manifest in the directly exposed organism but manifested in their offspring and were passed on for more than 14 generations. The study below now demonstrates that the effects of … Read more

Damaged mitochondria may cause 90%+ of Parkinson Disease (PD) cases

More evidence that yet another “incurable” condition is little more than energy deficit (due to mitochondrial dysfunction) in disguise. In this case the mitochondrial dysfunction was caused by accumulation of mitochondrial debris inside the cell, which has been repeatedly shown by other studies (and discussed on this blog) to be due primarily to chronic stress. … Read more

Vitamin D may treat (opioid) “addiction”

Interesting article, which corroborated the role of vitamin D as an anti-stress hormone. As vitamin D is an actual steroid, it is expected to have a role as neurosteroid as well, and as such influence behavior and habits, including pathological ones such as “addiction”. Why do I put “addiction” in quotes? Mostly because the totality … Read more

Stress ups cortisol/estrogen/prolactin, drops DHT, causes male infertility and prostate issues

If you try to discuss infertility with a fertility/reproductive specialist or an endocrinologist, and mention that chronic stress may be a factor in infertility, you will probably get laughed out of the room. This is not just speculation. This exact same thing happened to several friends and relatives who struggled to conceive, and it is … Read more