The government knows stress causes “learned helplessness” / depression

I have had discussions with numerous psychiatrists about the concept of “learned helplessness” (LH) and its relation to chronic stress. All of those doctors flatly denied that LH is a concept relevant to humans and argued that it is nothing more than a useful model of depression in animal studies, designed to evaluate animal exposure … Read more The government knows stress causes “learned helplessness” / depression

COVID-19/SARS may be due simply to serum PUFA and its peroxidation

During the last podcast with Danny Roddy, Dr. Peat and I discussed the role of elevated free fatty acids (FFA) in the blood as facilitators of viral infection. I opined that the hydrophilic nature of PUFA circulating in the blood increases the permeability of cells and allows for easier viral entry inside the cell and … Read more COVID-19/SARS may be due simply to serum PUFA and its peroxidation

Studies in animals often use stressful methods that produce invalid results

Back in 2012, when I first started writing about the benefits of steroids such as pregnenolone, I often got emails quoting the study below as evidence that pregnenolone and related steroids amplify instead of mitigate the stress response (HPA axis). https://www.ncbi.nlm.nih.gov/pubmed/17928160 “…We chose IP injection to assess neuroactive steroids effects at the central level because … Read more Studies in animals often use stressful methods that produce invalid results

Stress (cortisol) can cause ANY autoimmune condition by disrupting gut barrier

A great new study that is not afraid to point out the paradox between mainstream medicine’s claims of beneficial effects of cortisol and the reality of “autoimmune” conditions more often than not being associated with elevated levels of CRH, ACTH and cortisol. The role of CRH as a causative factor in a number of chronic … Read more Stress (cortisol) can cause ANY autoimmune condition by disrupting gut barrier

How chronic stress (cortisol) causes disease

Back in 2018 I did a post on a neat study that demonstrated how the presence of cellular (mitochondrial) fragments in the blood stream acts identically to the pituitary hormone ACTH and as such activates the HPA axis. The more cellular fragments are in the bloodstream the more intense the stress response from the adrenals. … Read more How chronic stress (cortisol) causes disease

Long work hours (stress) at the office cause hypertension and CVD

Many of my readers surely are familiar with the saying “work hard, play hard”. This mantra is at the core of the psychotic work culture of most “developed” countries and despite the assurances of doctors and public health officials that bad health is largely due to “bad luck” (e.g. genes) the skyrocketing rates of cardiovascular … Read more Long work hours (stress) at the office cause hypertension and CVD

Almost 40% of military women (and even more military males) are infertile

I think this study should dispel some of the myths about what being “fit” really means, and that being truly healthy or “fit” often are quite divergent paths. Infertility is actually one of the most reliable indicators of poor systemic health and predictor of future chronic disease (in both sexes). So, by that measure, almost … Read more Almost 40% of military women (and even more military males) are infertile

Serotonin causes anhedonia…and mental illness in general

As many of my readers know, anhedonia is one of the most pernicious symptoms of most mental disorders, and is perhaps the most resistant to therapy. It also happens to be one of the main triggers of attempted suicide, based on interviews with suicide survivors. I posted some threads in the past demonstrating that chronic … Read more Serotonin causes anhedonia…and mental illness in general

Down Syndrome (DS) cognitive handicap is due to (cellular) stress, may be reversible

If there is any disease that is currently considered incurable even in principles, it likely comes from the group of inherited/genetic disorders. Perhaps the most well-known one, due to rapidly rising incidence and thus publicity, is DS. Perhaps its most disabling aspect of DS is the cognitive dysfunction that manifest in such patients. The bulk … Read more Down Syndrome (DS) cognitive handicap is due to (cellular) stress, may be reversible

Rats can drive cars (to lower stress), befriend robot rats and help them when in trouble

Official/pathological science keeps sternly warning us not to anthropomorphize and to think of animals as nothing but dumb, soul-less automatons. Yet, there has been no evidence discovered in over 100 years of pathological science reign to support such a view. To the contrary, the studies below add even more to the already existing pile of … Read more Rats can drive cars (to lower stress), befriend robot rats and help them when in trouble