Blocking endotoxin may reverse cognitive decline of aging

Another study implicating endotoxin (LPS) and its associated receptor (TLR4) in a phenotype of aging considered “normal” by mainstream medicine, though it almost universally progresses into dementia territory with advancing age, to the point where 90%+ of people over 85 have at least moderate levels of dementia, even if not officially diagnosed with Alzheimer’s disease … Read more

Endotoxin (LPS) drives obesity, diabetes and CVD in young people

It looks like medicine is starting to change course on its attitude to endotoxin (LPS). After claiming that LPS is not an issue at all for any human with a functioning liver, a number of high profile studies have come out recently demonstrating chronic endotoxemia (even low-grade) is a causal factor in a number of … Read more

Cancer cells deprive immune cells of energy by devouring their mitochondria

In a description that could be a good plot for a horror-movie, the study below demonstrates that the immune failure often seen in cancer is, again, bioenergetic in origin. More specifically, the immune system cells are getting literally the energy (i.e. mitochondria) sucked out of them by cancer cells using tiny, nano-sized tentacles (a trunk … Read more

Endotoxin (LPS) may directly cause cancerization of normal cells

A very interesting new study, which confirms the direct causal role LPS has in chronic inflammatory diseases, and especially in cancer. In addition, the study may answer one of the long-standing critiques the medical establishment has always had against the hypothesis that LPS causes cancer (and other inflammatory diseases). Namely, various luminaries in the medical … Read more

PUFA required for periodontal disease, aspirin may help

It is common knowledge even among mainstream dentists that periodontal disease is caused by bacteria accumulating under the gums, which over time leads to chronic inflammation and thus destruction of both gum tissue and the alveolar/jaw bone underneath the gums. Another “new” discover is that microbiome overgrowth (and thus endotoxin/LPS production) is also involved and … Read more

Endotoxin (LPS) causes rheumatoid arthritis…and COVID-19

A great new study, which is perhaps the first to directly point the finger at endotoxin as perhaps the main cause of rheumatoid arthritis (RA). RA is an “autoimmune” condition and not only shares symptoms with other similar conditions such as Lupus, psoriasis, MS, etc, but now all of them are considered officially to be … Read more

Endotoxin (LPS) as a cause of liver disease, obesity and diabetes

The first article below is actually about praising fermented foods, which I don’t really agree with. So, I am posting it mostly because of the quote on endotoxin/LPS, which is a very rare finding in published medical literature since medicine does not recognize chronic, low-grade endotoxemia as a cause of any disease and claims the … Read more

Blocking the endotoxin receptor (TLR4) may prevent / treat hearing loss

I did a post a few months ago on the connection between tinnitus and serotonin – i.e. using anti-serotonin drugs may treat tinnitus. Since tinnitus is almost always a precursor state to hearing loss (and eventually deafness), the two conditions obviously go hand-in-hand and are likely caused by the same agent (e.g. serotonin). Since more … Read more

Endotoxin (LPS) may be the cause of fatal lung damage in COVID-19

Yet another study, which demonstrates that there is virtually no disease (acute of chronic, infections or not) where the infamous LPS does not play a causative role. As it turns out, the often fatal inflammatory reaction (cytokine storm) that usually kills patients with COVID-19 in ICU, is driven by endotoxin through activation of its TLR4 … Read more

Silica, present in most supplements/food, activates the endotoxin receptor (TLR4)

Many of my readers know about the health risks of silica – a substance doctors and pundits call completely “benign, present in virtually all commercially sold dietary supplements and also in most commercially sold food (even organic ones!). The most commonly used form commercially is silicon dioxide, which is essentially powdered glass! However, despite its … Read more