Malnutrition (fasting) or protein deficiency sufficient to cause diabetes

Yet another study that should give a pause to all health care providers who push their patients to lose weight at any cost – i.e. “lower is always better”, when it comes to BMI, as the dogma goes. Well, apparently not, according to the study below. The even more astounding fact is that it looks … Read more

SHBG may be a good test for liver (metabolic) health

A very good study, which probably runs counter to the “mantra” most bodybuilders adhere to – i.e. they would say one must keep their SHBG low in order to increase levels of “free” steroids since, the claim goes, only free steroids are active and capable of influencing cells. If SHBG is high, the claim is … Read more

PUFA cause obesity, diabetes, autism, Alzheimer’s disease, anxiety, and depression

The title is an actual quote from the article, so there is no editorializing on my part and it speaks volumes about how the authors feel about their findings. In addition, opposite effects were found for saturated fats, in this case coconut oil, which leads the authors to once again remind everybody that the medical … Read more

Even briefly elevated lactate is a “master” cause of chronic diseases

The title of the post actually does not do justice to how strongly the study authors word their statements in regards to lactate. The lead study author called lactate “a master regulator of carcinogenesis” (with “regulator” being a euphemism for “cause”, otherwise the study won’t get published), while the rest of the study goes to … Read more

Endotoxin (LPS) drives obesity, diabetes and CVD in young people

It looks like medicine is starting to change course on its attitude to endotoxin (LPS). After claiming that LPS is not an issue at all for any human with a functioning liver, a number of high profile studies have come out recently demonstrating chronic endotoxemia (even low-grade) is a causal factor in a number of … Read more

Lactate is a key driver of diabetes/obesity, by promoting inflammation

A great study, demonstrating that in diabetes (just as in cancer) the so-called Warburg Effect (aerobic glycolysis) is as much a cause of those degenerative conditions as it is an effect of. The study below demonstrated that increased intracellular lactate results in robust increase in systemic release of inflammatory cytokines, resulting in aggravation of systemic … Read more

Vitamin D may prevent/delay Type I diabetes

Vitamin D seems to be trying to take aspirin’s crown as a universal drug away. The study below is the latest evidence that this remarkable nutrient may have therapeutic effects in conditions that most doctors consider completely unrelated outside of vitamin D’s realm (e.g. calcium absorption). As per the study below, vitamin D joins niacinamide … Read more

DHT can stop aging of the pancreatic beta-cells (insulin-producing)

Another great study, which demonstrates that far from being a “villain” (in both males and females) DHT is in fact a crucial and positive factor in health. In this specific study below, it was demonstrated that DHT dose-dependently inhibited the aging/dysfunction of the pancreatic beta-cells, and the highest dose of DHT tested completely stopped that … Read more

Serotonin, SSRI drugs may be the cause of IBD, Parkinson’s, diabetes, etc.

A great new study that points the finger straight at serotonin (5-HT). It has been known since the 1940s that not only is 5-HT produced predominantly in the GI tract, but also that elevated serotonin levels are causally linked to a plethora of chronic conditions, especially various inflammatory bowel diseases (IBD) such as Crohn’s, ulcerative … Read more