Fasting ups estrogen & cortisol, decimates vitamin D, may cause diabetes

A really interesting study, which will likely generate more than a few hateful emails for my Inbox 🙂 Anyways, as the study demonstrates, fasting achieves these negative effects due to the elevated fatty acids working through PPAR activator PGC-1α, to activate both the estrogen receptor (ER) and glucocorticoid receptor (GR). So, aside from the important … Read more Fasting ups estrogen & cortisol, decimates vitamin D, may cause diabetes

Dietary PUFA in childhood causes diabetes and irreversible (male) infertility

A great study, which corroborates the discussion in another recent post of mine on PUFA’s role in infertility and insulin-resistance / diabetes. However, the study below found that the infertility caused by dietary PUFA exposure were NOT reversible upon discontinuation of the high-fat (both PUFA and MUFA) diet, while previous studies found that the infertility … Read more Dietary PUFA in childhood causes diabetes and irreversible (male) infertility

Aromatase inhibitor (AI) + DHT combo may reverse kidney disease (CKD)

A truly great study for a number of reasons. First, it cites extensive evidence that male patients with diabetes (both types) have low androgens and high estrogen (estradiol). The association between this endocrine abnormality and the severity of diabetes is apparently quite strong, yet it is virtually unknown in endocrinology circles. In fact, there have … Read more Aromatase inhibitor (AI) + DHT combo may reverse kidney disease (CKD)

Statins may cause insulin resistance by depleting vitamin K

A great study, which both highlights the dangers of statins while also providing a plausible mechanism for those side effects that both FDA and Big Pharma vehemently continue to dispute. This plausible mechanism involves the inhibition of vitamin K2 (MK-4) synthesis, which requires the same enzymes that synthesize cholesterol. As the authors themselves state, vitamin … Read more Statins may cause insulin resistance by depleting vitamin K

High-carb (65%-85%) diets therapeutic in diabetes

Another myth of mainstream medicine continues to (slowly) crumble. The myth of diabetes as the “sugar disease” may be still alive but the evidence against it is quickly mounting. Perhaps the only thing still preventing it from collapsing overnight is the large numbers of Paleo-diet supporters who currently dominate the blogosphere and serve as a … Read more High-carb (65%-85%) diets therapeutic in diabetes

PUFA makes girls fat / lazy / diabetic and exercise futile

Just a few minutes ago I made a post about PUFA (from nuts) increasing risk of diabetes. I just came across another very similar study below. It found that PUFA consumption, in both mice and humans, makes them fat and highly sedentary while also increasing their diabetes risk. MUFA and SFA had no such effects … Read more PUFA makes girls fat / lazy / diabetic and exercise futile

Nut consumption may cause diabetes even without obesity

Such are the findings of this intriguing study, and I suspect the authors probably “massaged” the data a bit in order to avoid getting their study rejected by the peer-review committee. Cases of diabetes II without the presence of obesity are extremely rare, so the finding that nut consumption robustly increases diabetes risk and blood … Read more Nut consumption may cause diabetes even without obesity

PUFA may drive obesity, insulin resistance, liver issues in diabetes II patients

Yet another study where the message is clear – there is nothing “essential” about the PUFA we are bombarded with from all directions be that diet, medical interventions, household products, etc. What makes this study particularly relevant is that PUFA ingestion actually is promoted as one of the healthiest ways to keep weight at bay, … Read more PUFA may drive obesity, insulin resistance, liver issues in diabetes II patients

High levels of DHT may reduce diabetes risk

The title says it all, as the study is quite clear. DHT “…was most consistently associated with a lower level of insulin resistance and lower risk of incident diabetes” in the words of the study’s lead author. The current darling of “aging/obese male” treatments – testosterone (T) – was not associated with lower insulin resistance … Read more High levels of DHT may reduce diabetes risk

Pre-natal Viagra use causes offspring hypertension and maternal diabesity

The study looks weird at first glance – why would pregnant women take Viagra? After all, it is a drug initially developed for treating hypertension and erectile dysfunction (ED) in men. Well, the same misguided idea of using nitric oxide (NO) promoting drugs like Viagra to induce vasodilation has now been applied to the field … Read more Pre-natal Viagra use causes offspring hypertension and maternal diabesity