DHT better (and safer) than testosterone for improving blood pressure, insulin levels

A great human study on the beneficial effects of androgens for a variety of metabolic biomarkers associated with insulin resistance and diabetes II. The only gripe I have with this study is that they claim it was conducted with “healthy” men when in reality all men had low plasma total testosterone (PTT), which of course … Read more DHT better (and safer) than testosterone for improving blood pressure, insulin levels

Even mainstream medicine admits many claims about sugar are myths

It is always nice to see when a outpost of mainstream medicine tries to set the record straight on something as controversial as refined sugar. My personal favorites are the myths on sugar and causal links to diabetes / cancer. Apparently, there is solid evidence those links are myths. Yet, every doctor I ever met … Read more Even mainstream medicine admits many claims about sugar are myths

Stress (cortisol) as the driver of hyperglycemia in type II diabetes

To most of my readers, the title of the post may seem like something completely obvious and not deserving explanation of clarification. However, according to mainstream medicine (until now, at least) cortisol does not really have a causative role either in the development of diabetes type II or in its various manifestations such as obesity, … Read more Stress (cortisol) as the driver of hyperglycemia in type II diabetes

Glycine (and leucine) can treat fatty liver (NAFLD and NASH)

A great new study that demonstrates the strong protective effects of glycine, alone or in combination with leucine, on preventing/treating various forms of fatty liver disease, as well as the obesity that often accompanies these conditions. One of the strong points of the study is that it also established a minimum daily dosage needed to … Read more Glycine (and leucine) can treat fatty liver (NAFLD and NASH)

Fasting ups estrogen & cortisol, decimates vitamin D, may cause diabetes

A really interesting study, which will likely generate more than a few hateful emails for my Inbox 🙂 Anyways, as the study demonstrates, fasting achieves these negative effects due to the elevated fatty acids working through PPAR activator PGC-1α, to activate both the estrogen receptor (ER) and glucocorticoid receptor (GR). So, aside from the important … Read more Fasting ups estrogen & cortisol, decimates vitamin D, may cause diabetes

Dietary PUFA in childhood causes diabetes and irreversible (male) infertility

A great study, which corroborates the discussion in another recent post of mine on PUFA’s role in infertility and insulin-resistance / diabetes. However, the study below found that the infertility caused by dietary PUFA exposure were NOT reversible upon discontinuation of the high-fat (both PUFA and MUFA) diet, while previous studies found that the infertility … Read more Dietary PUFA in childhood causes diabetes and irreversible (male) infertility

Aromatase inhibitor (AI) + DHT combo may reverse kidney disease (CKD)

A truly great study for a number of reasons. First, it cites extensive evidence that male patients with diabetes (both types) have low androgens and high estrogen (estradiol). The association between this endocrine abnormality and the severity of diabetes is apparently quite strong, yet it is virtually unknown in endocrinology circles. In fact, there have … Read more Aromatase inhibitor (AI) + DHT combo may reverse kidney disease (CKD)

Statins may cause insulin resistance by depleting vitamin K

A great study, which both highlights the dangers of statins while also providing a plausible mechanism for those side effects that both FDA and Big Pharma vehemently continue to dispute. This plausible mechanism involves the inhibition of vitamin K2 (MK-4) synthesis, which requires the same enzymes that synthesize cholesterol. As the authors themselves state, vitamin … Read more Statins may cause insulin resistance by depleting vitamin K

High-carb (65%-85%) diets therapeutic in diabetes

Another myth of mainstream medicine continues to (slowly) crumble. The myth of diabetes as the “sugar disease” may be still alive but the evidence against it is quickly mounting. Perhaps the only thing still preventing it from collapsing overnight is the large numbers of Paleo-diet supporters who currently dominate the blogosphere and serve as a … Read more High-carb (65%-85%) diets therapeutic in diabetes

PUFA makes girls fat / lazy / diabetic and exercise futile

Just a few minutes ago I made a post about PUFA (from nuts) increasing risk of diabetes. I just came across another very similar study below. It found that PUFA consumption, in both mice and humans, makes them fat and highly sedentary while also increasing their diabetes risk. MUFA and SFA had no such effects … Read more PUFA makes girls fat / lazy / diabetic and exercise futile