Tag: inflammation

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Statins damage muscles by increasing endotoxin/LPS absorption and inhibiting glucose metabolism

Statin drugs that lower cholesterol are perhaps the most widely prescribed medications globally. Despite their effectiveness at…

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Interfering with mitochondrial dynamics causes cancer (by driving inflammation); no carcinogen/mutation required!

One of the rare studies that quietly lets the truth out in the open. Namely, that cancer…

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Blocking the endotoxin/LPS receptor (TLR4) prevents brain damage from concussion

Yet another incurable and deadly condition tied to inflammation and endotoxin, and apparently easily preventable by blocking…

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Eliminating sugar (sucrose) from the diet leads to diabetes, as well as gut and liver inflammation

This study will probably rile up the low-carb legions, who seem to have completely taken over the…

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High-fat diet causes depression by increasing inflammation; low-dose aspirin reverses both

The evidence for depression as an inflammatory disease is pretty strong at this point, and several pharma…

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An inflammatory PUFA metabolite drives liver fibrosis (cirrhosis) by poisoning mitochondria

Ray wrote extensively about the toxicity of polyunsaturated fatty acids (PUFA) , particularly their propensity to undergo lipid peroxidation…

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A constipation drug can treat kidney disease, likely by lowering endotoxin/LPS

Chronic kidney disease (CKD) is conventionally managed with blood pressure control, protein restriction, and phosphate binders. Constipation…

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Endotoxin/LPS can cause spontaneous abortion by raising nitric oxide (NO)

I am posting this study as a kind of a follow-up on the one I posted just…

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High-fat diet ups cortisol/serotonin (5-HT), hinders 5-HT deactivation, causes leaky gut and systemic inflammation

I am sure I will get a lot of hate-mail about this, but frankly this is not…

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Plasma endotoxin/LPS is a reliable predictor of mortality in hospitalized children

A great study, whose findings (I believe) can be plausibly extended to all hospitalized patients given the…