Tag: pyruvate
Estrogen and cortisol inhibit mitochondrial oxidation, vitamin E reverses the inhibition
More specifically, those steroids inhibit NADH (also known as DPNH) oxidation in the mitochondria, which shifts the…
Reduced availability/oxidation of glucose sufficient to cause heart failure (HF)
Yet another “mysterious” idiopathic condition turns out to be nothing but metabolic dysregulation in disguise. Also, unlike…
Epilepsy/seizures caused by energetic deficit leading to calcium overload
Yet another study demonstrating that not only is a chronic, “incurable” disease of unknown origin treatable but…
Niacinamide + pyruvate may treat glaucoma (human study)
Some excellent results from a human clinical trial. Namely, a combination of 3g niacinamide and 3g (calcium)…
Reduced pyruvate and/or increased lactate drive heart failure
I just did a post on the role of reduced glucose metabolism, lower pyruvate/NAM/NAD and elevated lactate…
Glaucoma likely a metabolic disease, treatable by pyruvate and/or niacinamide
About a year ago, a publication came out that demonstrated therapeutic effects of raising the (mitochondrial) NAD/NADH…
Glucose is anabolic for thymus, opposes catabolic effects of cortisol
As most of my readers know, cortisol is a highly catabolic steroid and one of the main…