Tag: PUFA
An inflammatory PUFA metabolite drives liver fibrosis (cirrhosis) by poisoning mitochondria
Ray wrote extensively about the toxicity of polyunsaturated fatty acids (PUFA) , particularly their propensity to undergo lipid peroxidation…
Aging driven by PUFA and its peroxidation; vitamin E, PUFA avoidance, eating SFA may delay/reverse aging
For decades, mainstream medicine has promoted the idea that reactive oxygen species (ROS) are uniformly harmful and that…
Rapid fat loss can cause diabetes and liver disease, likely due to systemic exposure to free fatty acids
When people asked Ray during interviews and in emails about weight loss, he always cautioned that rapid…
Omega-6 and omega-3 PUFA promote inflammatory pathways at the genomic level; SFA do not
As my readers know, one of the main inflammatory effects of PUFA is due to their conversion…
PUFA almost fully blocks protein synthesis and the effect is correlated with unsaturation; SFA do not
Another study demonstrating direct negative effect of PUFA on human health. Namely, inhibition by PUFA of protein…
PUFA/MUFA trigger serotonin release, platelet aggregation independently of downstream metabolites; SFA do not
One of the sneaky arguments that mainstream makes in favor of PUFA is that while they have…
High-fat/low-carb diet causes systemic inflammation, impairs gut barrier, aggravates inflammatory bowel disease (IBD)
Another “controversial” study, which adds even more evidence to the hypothesis that low-carb diets (and by extension,…
PUFA is incompatible with and directly toxic to mammalian mitochondria
This is one of the few studies that presents direct and largely indisputable biochemical evidence for the…
Linoleic acid (an omega-6 PUFA) confirmed as direct driver of many (all?) cancers
It looks like medicine is finally starting to wake up to the fact that PUFA is anything…
PUFA/endotoxin cause Alzheimer Disease (AD), the plaques beta-amyloid/tau are protective
One of the biggest failures of medicine to date is prevention and treatment of AD. As I…