COVID-19/SARS may be due simply to serum PUFA and its peroxidation

During the last podcast with Danny Roddy, Dr. Peat and I discussed the role of elevated free fatty acids (FFA) in the blood as facilitators of viral infection. I opined that the hydrophilic nature of PUFA circulating in the blood increases the permeability of cells and allows for easier viral entry inside the cell and … Read more COVID-19/SARS may be due simply to serum PUFA and its peroxidation

America’s favorite oil causes diabetes, obesity, autism, and liver / brain disease

A series of shockingly direct studies that do not shy away from pointing the finger at the real villain in modern public health history – PUFA, and more specifically the “essential” linoleic acid (LA). As the studies demonstrate, soy oil has strikingly detrimental effects on metabolic health and the main culprit, at least as far … Read more America’s favorite oil causes diabetes, obesity, autism, and liver / brain disease

PUFA are immunosuppressive, fasting and protein restriction (possibly) even more so

Several great studies, which quickly illustrate the connection between PUFA, immune system, estrogen, cortisol, cancer and the protective role vitamin A/E play as well as their likely mechanism(s) of action. As I mentioned on one of the first podcasts with Danny Roddy, the role of PUFA as immunosuppressants is actually well-known in the organ transplant … Read more PUFA are immunosuppressive, fasting and protein restriction (possibly) even more so

SFA / MUFA are preferentially oxidized, while PUFA are stored/accumulated

Just a quick post in response to some of the hate mail I keep getting on a daily basis in regards to the body’s discriminatory treatment of various fat types. According to various proponents of keto diets, fasting, etc the organism has no preference for one type of fat or another in terms of oxidation … Read more SFA / MUFA are preferentially oxidized, while PUFA are stored/accumulated

PUFA and serotonin promote each other, and likely cause mental illness

I neat new study that draws a direct parallel between PUFA-driven inflammation, serotonin and depression. As the study demonstrated, high levels of the PUFA arachidonic acid (AA) are highly correlated with lower density (expression) of the serotonin transported (SERT, 5-HTT), and the relationship is actually causative in both directions (AA<->serotonin). This results in increased serotonin … Read more PUFA and serotonin promote each other, and likely cause mental illness

Cholesterol and saturated fat are anabolic; PUFA/MUFA akin to chemical castration

A pair of interesting study and a commentary in the highly respected Journals of Gerontology. Namely, higher cholesterol intake is associated with much higher lean muscle mass accrual as a result of weight lifting. Interestingly, higher protein intake was not. Even more interestingly, and much to the chagrin of the medical industry, the increased dietary … Read more Cholesterol and saturated fat are anabolic; PUFA/MUFA akin to chemical castration

PUFA, from formula feeding or maternal obesity, may cause leukemia

Another great study, and one of the few that dares point the finger at medicine’s Holy Grail – the “essential fatty acids”. As the study aptly says, high levels of PUFA in the blood and especially higher levels of linoleic acid predict subsequent development of acute lymphoblastic leukemia (ALL) in children. While the study is … Read more PUFA, from formula feeding or maternal obesity, may cause leukemia

PUFA (metabolites) drive heart failure and possibly diabetes

Over the years I have posted a number of studies on the roles of PUFA metabolites such as prostaglandins and leukotrienes in many chronic conditions including cancer, Alzheimer, Parkinson, ALS, MS, CVD, etc. For those that are new to this issue, COX enzymes are responsible for prostaglandin synthesis while LOX enzymes are responsible for leukotriene … Read more PUFA (metabolites) drive heart failure and possibly diabetes

Obesity increasing; is NOT due to the cliche urban, gluttonous, sedentary lifestyle

I just made a post questioning the universal dogma peddled by every doctor – i.e. “eat less, move more”. http://haidut.me/?p=127 The study below shows that obesity rates are rising worldwide. A doctor would immediately suggest that this is due to urban overpopulation, with hordes of gluttonous, chips-eating, video-game-playing, sedentary, bored people who do little more … Read more Obesity increasing; is NOT due to the cliche urban, gluttonous, sedentary lifestyle

Allopregnanolone deficiency during pregnancy causes autism

Yet another study that links prenatal stress with the offspring developing autism. The rates of autism have been steadily rising over the last 3 decades but the medical profession claims this is simply due to better diagnostic methods. The fact that the health of general population, and especially young women of child-bearing age, is declining … Read more Allopregnanolone deficiency during pregnancy causes autism