PUFA are remarkably estrogenic, toxic to the ovaries

One of the few studies that looks into the issue of whether the xenoestrogenic burden we are exposed to 24×7 in Western countries is due entirely to synthetic, industrial chemicals or if there is more to the story. Well, there is definitely more to the story, and the additional evidence we have from the study … Read more

SSRI drugs decrease androgens / progestogens, increase estrogens

As hard as it is to believe, this is the actual title of the study – i.e. SSRI drugs are bonafide endocrine disruptors. As it turns out, all of the six most-prescribed SSRI drugs the study looked at behaved not only as inhibitors of gonadal androgen synthesis (e.g. testosterone, DHT), but also adrenal androgens (DHEA) … Read more

Some aromatase inhibitors (AI) are estrogenic

I have long suspected this considering the peculiar side effects of some AI drugs, but was not able to find concrete evidence…until now. The study below demonstrates that one of the most widely used AI – anastrozole – is a potent estrogen receptor activator/agonist, and at low concentrations too. At higher concentrations, the estrogenic effects … Read more

Simple, non-invasive test for adrogenic / estrogenic tone

One of the core issues in modern endocrinology is the relatively weak correlation between serum levels of steroids and the overall activity in the organism associated with a particular steroid. For example, post-menopausal women have very low levels of estradiol yet very high whole-body estrogenicity due to the deficiency of progesterone that menopause induces. Even … Read more

Endocrine disruptors (BPA) can cause autism several generations later

In one of his recent newsletters, as well several KMUD interviews, Peat mentioned that the effects of GMO foods and other environmental toxins would not be immediately visible. In fact, they would take several generations to manifest and by the say third, forth, fifth generations we would start seeing things like sterility, cancer, neurodenegerative disease, … Read more