Prostate levels of androgens/DHT drastically lower in prostate cancer patients

Yet another study, which raises serious doubts about the so-called “androgen hypothesis” of prostate cancer (PC). The study found that androgen levels, and especially DHT, are drastically (90%+) lower in PC than in people with benign prostate hyperplasia (BPH). In fact, 1/3 of the PC patients included in the study had undetectable DHT levels in … Read more

Fasting / stress decimate gonadal steroidogenesis, with no effect on blood cortisol

A very interesting and very “controversial” (read: inconvenient truth) study, since it shows beyond reasonable doubt that even brief (4 days) fasting is a form of severe stress, at least when it comes to endocrine health. The study may also provide answers to various endocrine “mysteries” becoming more common among the male population of “developed” … Read more

DHT may treat thyroid cancer

Yet another “non-endocrine” tumor turns out to be anything but. Thyroid cancer rates have been rising for the last 30 years and parallel the increase in diagnoses of its likely precursor – i.e.  the “autoimmune” disorder Hashimoto Disease. While there is solid evidence implicating endocrine disruptors, especially from plastics (proven to have estrogenic, anti-androgenic, and … Read more

DHT as anti-inflammatory as cortisol, but without the side effects

As most of my readers know, glucocorticoids (synthetic or bioidentical) are widely used clinically and there is hardly a chronic conditions for which they are not prescribed even if only for managing brief “acute exacerbations”. Despite mainstream medicine doing everything it can to conceal the massively pathogenic effects of those steroids, even seasoned doctors would … Read more

DHT can stop aging of the pancreatic beta-cells (insulin-producing)

Another great study, which demonstrates that far from being a “villain” (in both males and females) DHT is in fact a crucial and positive factor in health. In this specific study below, it was demonstrated that DHT dose-dependently inhibited the aging/dysfunction of the pancreatic beta-cells, and the highest dose of DHT tested completely stopped that … Read more

Scoliosis (even in females) may be driven by low androgen levels, DHT may treat it

I am posting about this condition as it seems recently its numbers have absolutely exploded in the general population. Scoliosis used to be a relatively uncommon condition, usually present in adults over the age of 50. Mainstream medicine has no explanation for its possible causes, but suspects inflammation is involved. The study below suggests that … Read more

Stress ups cortisol/estrogen/prolactin, drops DHT, causes male infertility and prostate issues

If you try to discuss infertility with a fertility/reproductive specialist or an endocrinologist, and mention that chronic stress may be a factor in infertility, you will probably get laughed out of the room. This is not just speculation. This exact same thing happened to several friends and relatives who struggled to conceive, and it is … Read more

DHT, not T, likely the “active” androgen in heart and brain

Interesting study, done on baboons (so should have good relevance for humans), demonstrating that the cardiovascular system (CVS) exclusively accumulates and recognizes (at the receptor level) DHT, instead of testosterone (T). In fact, the androgen receptor in CVS is so structurally different it apparently cannot even bind T. Recent studies with ALS patients suggest the … Read more

Estrogens cause obesity / PCOS in women, DHT is protective

Female obesity and the closely related condition PCOS are perhaps the female equivalent of the so-called “androgen hypothesis” for balding and prostate cancer in men, as the female version of this hypothesis not only blames androgens for these conditions but specifically singles out DHT as the main “villain”. The mainstream medical dogma is that a … Read more

Low DHT can cause hypogonadism symptoms even in eugonadal men

Seemingly contradictory title, but the study findings are pretty clear. Namely, even in males with normal testosterone levels there is a direct inverse relationship between DHT levels and symptoms of hypogonadism such as sexual dysfunction and “aging male” syndrome. For every 10% increase in DHT levels there was a 4.67% decrease in hypogonadism symptoms of … Read more