Cardiolipin supplementation may reverse signs of aging

One of the key features of aging is the decline in mitochondrial function (metabolism), and that fact is widely recognized even by mainstream medicine. However, doctors still claim that the relationship between metabolic decline and aging has not be elucidated and a causative link cannot be established (yet). In other words, we don’t know if … Read more Cardiolipin supplementation may reverse signs of aging

Aspirin protects mitochondria from inflammation and aging

The good news about aspirin just never seem to stop. While the anti-inflammatory effects of aspirin are well-known, mainstream medicine like to explain them away with the limited (and frankly primitive) mechanism of COX inhibition alone. If aspirin happens to achieve some other beneficial health effects, the doctors always try to either frame it in … Read more Aspirin protects mitochondria from inflammation and aging

“Anti-aging” hormone (hGH) may actually shorten life

The duo of hGH/IGF-1 does not need an introduction. Hardly a day passes without some ad on TV promoting the latest and greatest product that “naturally boosts” either hGH or IGF-1 levels. The two hormones have an almost perfect correlation – each one inducing the endogenous synthesis of the other. Clinics catering to the super … Read more “Anti-aging” hormone (hGH) may actually shorten life

Striking accumulation of PUFA in aged cells

Peat has written many times about the changes that occur in “aged” cells. Those changes are virtually indistinguishable from the ones that occur in “sick” cells and are characterized by reduced mitochondrial number/size and a shift in lipid composition away from saturated and towards unsaturated fats. The crucial mitochondrial lipid enzyme cardiolipin (CL) comprises at … Read more Striking accumulation of PUFA in aged cells

Vitamin E, anabolic / catatoxic steroids, egg yolks stop soft tissue calcification and (maybe) even aging

A great series of studies performed in the 1960s, with Hans Selye spearheading most of the investigations. It is amazing how much was known about human disease and aging, and how much of that knowledge has been so thoroughly forgotten to the point that doctors nowadays have never even heard of the term “catatoxic”. One … Read more Vitamin E, anabolic / catatoxic steroids, egg yolks stop soft tissue calcification and (maybe) even aging

Metabolic dysfunction is a primary cause of aging and its symptom Alzheimer Disease (AD)

As it seems, not all hope is lost when it comes to mainstream medicine. Just a few days ago I posted about a landmark human study with AD demonstrating that the a low daily dose of the cheap, unpatentable chemical methylene blue (MB) may stop AD. LSD may do the same, and both MB and … Read more Metabolic dysfunction is a primary cause of aging and its symptom Alzheimer Disease (AD)

Increasing metabolism may reverse Alzheimer Disease (AD) and general aging

Yet another study demonstrating the remarkable parallels between the decline in function (metabolism) and the structural abnormalities that occur not only in specific pathologies such as AD but also in the generalized degradation known as “aging”. FDA currently does not recognize aging as a disease, but the evidence for it is rapidly accumulating. Just a … Read more Increasing metabolism may reverse Alzheimer Disease (AD) and general aging

Aging likely caused by decreased respiration / metabolism, not genetic mutations

It looks like after a century of utter idiotism in biology and medicine, those two disciplines may finally be getting on the right course. Despite the fact that the “rate of living” theory is still the dominant theory of aging in the halls of academia, a new generation of scientists is emerging that is not … Read more Aging likely caused by decreased respiration / metabolism, not genetic mutations

Estrogen and cortisol, not androgens, suppress immunity

There is a very famous theory in reproductive biology still considered the dominant one in its field. Namely, males have to accept a trade-off between androgen levels and immunity. It is known as the immunocompetence handicap hypothesis (ICHH). Higher androgen levels, the theory goes, allow the male to (physically) outcompete other males around him for … Read more Estrogen and cortisol, not androgens, suppress immunity

PUFA are immunosuppressive, fasting and protein restriction (possibly) even more so

Several great studies, which quickly illustrate the connection between PUFA, immune system, estrogen, cortisol, cancer and the protective role vitamin A/E play as well as their likely mechanism(s) of action. As I mentioned on one of the first podcasts with Danny Roddy, the role of PUFA as immunosuppressants is actually well-known in the organ transplant … Read more PUFA are immunosuppressive, fasting and protein restriction (possibly) even more so