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Niacinamide as treatment for scleroderma (systemic sclerosis)

Yet another “incurable” disease has been demonstrated to be nothing more but energetic deficiency in disguise. According…

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DHT restores anabolism / vitality / sexuality even in 90+ y.o. males

A great study, a true blast from the (better) past, when androgenic steroids and especially DHT were…

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Androgens (e.g. DHT) curative even for treatment-resistant breast cancer

As many of my readers know, back in the “good ol’ days” (when medicine was slightly less…

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Endotoxin (LPS) as a cause of systemic inflammation seen in obesity

Yet another study implicating the great villain of systemic health – endotoxin / LPS. It is well-known…

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Endotoxin behind the mortality of Black Death and 1918 Flu pandemics

As many of my readers know, many/most people dying from COVID-19 develop either sepsis and/or respiratory failure….

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Sugar (sucrose) lowers stress-induced cortisol

Just a quick post to give some props to the much-vilified sucrose. The study below demonstrates that…

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Some aromatase inhibitors (AI) are estrogenic

I have long suspected this considering the peculiar side effects of some AI drugs, but was not…

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Even “non-carcinogenic” estrogens can cause cancer

I know, the title is a “paradox”, but this is truly what the article discusses. By now,…

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Reduced pyruvate and/or increased lactate drive heart failure

I just did a post on the role of reduced glucose metabolism, lower pyruvate/NAM/NAD and elevated lactate…

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Glaucoma likely a metabolic disease, treatable by pyruvate and/or niacinamide

About a year ago, a publication came out that demonstrated therapeutic effects of raising the (mitochondrial) NAD/NADH…