Tag: tlr4
PUFA peroxidation byproduct and endotoxin/LPS drive ALS and are reliable predictors of its lethality
Yet another lethal condition, for which no known treatment exists or is even in the pharma drug…
Blocking the endotoxin/LPS receptor (TLR4) prevents brain damage from concussion
Yet another incurable and deadly condition tied to inflammation and endotoxin, and apparently easily preventable by blocking…
Inosine directly binds and blocks the endotoxin/LPS receptor (TLR4)
Inosine is an endogenous purine and a breakdown product of ATP. Elevated inosine levels are observed in…
Endotoxin/LPS drives esophageal cancer
One of the few studies to directly implicate endotoxin (also known as LPS) in cancer progression. While…
Parkinson Disease (PD) akin to infectious disease – driven by endotoxin, damaged mitochondria
Yet another study demonstrating that there is no need for genes or any other hereditary mechanism to…
Blocking endotoxin (TLR4) may prevent death from viral infections (COVID-19/ARDS)
Almost a decade ago I posted about a “rogue” study which had the audacity to suggest that…
Serum endotoxin level is a reliable biomarker of liver disease
It looks like the interest in gut-derived pathogenic substances is steadily increasing in the medical field. After…
Endotoxin (LPS) – a reliable biomarker of cardiovascular disease (CVD)
It looks like more and more medical groups are waking up to the important role LPS plays…
Endotoxin (LPS) may drive kidney damage in diabetes type II
Not much of a news, but I like adding to the, already big, pile of evidence that…
Another “paradox” – glucocorticoids cause inflammation, insulin blocks it
As many of my readers know, I am not a fan of the ubiquitous usage of both…