Tag: mitochondria

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An inflammatory PUFA metabolite drives liver fibrosis (cirrhosis) by poisoning mitochondria

Ray wrote extensively about the toxicity of polyunsaturated fatty acids (PUFA) , particularly their propensity to undergo lipid peroxidation…

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Starving cancer of glucose is a BAD idea

For years, mainstream oncology has been pushing the idea of “starving cancer” by depriving tumors of glucose….

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A constipation drug can treat kidney disease, likely by lowering endotoxin/LPS

Chronic kidney disease (CKD) is conventionally managed with blood pressure control, protein restriction, and phosphate binders. Constipation…

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Tuinone – Liquid Product with Thymoquinone

The topic of quinones probably does not need an extensive introduction in light of Ray’s extensive writings…

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Even mild inhibition of oxidative metabolism may cause szhizophrenia, naicinamide reverses it

An excellent set of studies, demonstrating that another “mysterious” and “genetically-predisposed” condition can be caused entirely by…

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Constipation drug improves mitochondrial function, and ameliorates kidney disease, likely by lowering endotoxin/LPS

In the archive threads of emails Ray answered from numerous people with chronic kidney disease, one consistent…

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A shift from oxidative toward anaerobic metabolism increases nitric oxide (NO) and lactate and drives migraines

Ray mentioned the topic of migraines many times in his articles. He implicated estrogen, serotonin, NO and…

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“Gulf War Syndrome” likely curable; it is driven by metabolic dysfunction and inflammation, not neuron damage

Some good news just in for the holidays. For decades, military veterans with this conditions have been…

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Mictochondrial NAD+ levels drive liver regeneration

Given the prevalence of liver disease – NAFLD, NASH, cirrhosis and even liver cancer – in the…

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Wasting syndrome (cachexia) driven by low metabolism/NAD+; can be blocked/reversed

One of those articles that fully corroborates Ray’s views that metabolism is central not only to “function”,…