Oral vitamin D3 may treat steroid-driven hair loss

A very interesting study, which demonstrates that a relatively low (5,000 IU) oral daily dose of vitamin D3 for 6 months, may be able to treat gender-specific (driven by steroids) hair loss. Now, the study participants were all female, with female-pattern hair loss (FPHL), however the findings should be applicable to the other gender as … Read more

Vitamin D may prevent/delay Type I diabetes

Vitamin D seems to be trying to take aspirin’s crown as a universal drug away. The study below is the latest evidence that this remarkable nutrient may have therapeutic effects in conditions that most doctors consider completely unrelated outside of vitamin D’s realm (e.g. calcium absorption). As per the study below, vitamin D joins niacinamide … Read more

Vitamin D3 anabolic, calcitriol catabolic for muscle/thymus

Several great studies, which will probably do little to calm down the controversy that seems to be brewing lately in the blogosphere over whether supplementing with vitamin D3 is beneficial or not. Namely, the last study below demonstrated direct muscle-anabolic effects from supplementation with vitamin D3 (cholecalciferol), in direct opposition to the known catabolic effects … Read more

Vitamin D may treat (opioid) “addiction”

Interesting article, which corroborated the role of vitamin D as an anti-stress hormone. As vitamin D is an actual steroid, it is expected to have a role as neurosteroid as well, and as such influence behavior and habits, including pathological ones such as “addiction”. Why do I put “addiction” in quotes? Mostly because the totality … Read more

High PTH, low vitamin D implicated in bipolar disorder (BD)

A great study highlighting once again the importance of calcium, vitamin D and especially the pro-inflammatory parathyroid hormone (PTH) for mental health. While there are many studies (both observational and intervention ones) examining the role of vitamin D in mental health, this is one of the very few looking into the role of PTH. It … Read more

Vitamin D (topical) safe and effective for removing scars

A neat human study, which demonstrates that topical treatment with vitamin D may treat even large scars that have been present on the skin for years. Many people have such scars as a result of surgery, trauma, chemical/heat burns, radiation, etc. As the study says, the typical treatment is with cortisol injections, however the effectiveness … Read more

Vitamin D deficiency impairs muscles by lowering energy production

Perhaps this study below will put some of the arguments against vitamin D supplementation to rest. It demonstrated up to 40% reduction of energy production in the muscles of animals deficient in vitamin D, in spite of unchanged number/size/density of mitochondria inside the cells. In addition, it demonstrated decrease in lean mass in the deficient … Read more

Vitamin D can force cancer cells to differentiate back into normal

Danny and I already discussed this topic on a recent podcast, but I decided to post the studies anyways, considering how important the topic is. While progesterone and testosterone are the most well-known differentiating factors in humans, the role of vitamin D has gone largely unnoticed. The studies below demonstrate that vitamin D is a … Read more

Vitamin D prevents cortisol-induced depression and…inflammation

A great study for a number of reasons. First, it discussed openly that in animal research circles cortisol administration is considered an official and reliable method of causing major depression. As the article states, for some reason human medical circles have been unwilling to accept the stress-depression causal link and continue to argue that stress … Read more

Vitamin D is anti-catabolic / anabolic, protects liver from cortisol injury

In a recent post of mine I discussed the effects of cortisol on various aminotransferases (especially TAT), their role as biomarkers of catabolism, and how inhibitors of said aminotransferases have a potent anti-catabolic / anabolic effects. In that same post, I also described how cortisol (a catabolic steroid) is, naturally, a potent inducer of those … Read more