Blocking serotonin may treat allergies and inflammatory diseases

The bad news for serotonin (5-HT) just keeps accumulating. Aside from its well-known (outside of medical office, of course) effects on causing pretty much any mental illness defined in DSM V, as well as fibrosis in any organ/tissue unfortunate enough to be exposed to 5-HT now we can add infectious disease, allergies and inflammatory diseases. … Read more Blocking serotonin may treat allergies and inflammatory diseases

Serotonin causes anhedonia…and mental illness in general

As many of my readers know, anhedonia is one of the most pernicious symptoms of most mental disorders, and is perhaps the most resistant to therapy. It also happens to be one of the main triggers of attempted suicide, based on interviews with suicide survivors. I posted some threads in the past demonstrating that chronic … Read more Serotonin causes anhedonia…and mental illness in general

Gut serotonin (due to bacteria) is the master regulator of metabolism, insulin sensitivity, and weight

Over the last year I posted a number of studies demonstrating strong link between serotonin and chronic conditions such as obesity, insulin resistance, and even diabetes. https://www.nature.com/articles/s41366-018-0047-8 https://medicalxpress.com/news/2018-03-obesity-trigger-human-gut.html However, when those studies came out the medical authorities immediately countered with the argument that it is not serotonin that is the culprit but changes in the … Read more Gut serotonin (due to bacteria) is the master regulator of metabolism, insulin sensitivity, and weight