sirtuin

Keto (low-carb) diet causes heart fibrosis, blocks mitochondrial biogenesis

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The bad news for the low-carb / keto community keep piling on. There are a number of posts on this blog about studies demonstrating insulin resistance, diabetes, obesity and even sarcopenia as a result of low-carb diets or their close mimetic known as intermittent fasting. Now, the study below provides the first direct evidence that … Read more Keto (low-carb) diet causes heart fibrosis, blocks mitochondrial biogenesis

SIRT1 is a key promoter of leukemia and other blood cancers

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SIRT1 (one of the sirtuin genes) is currently one of the stars in the nutritional/medical blogosphere. As far as back as 2004, SIRT1 was promoted as a key regulator of longevity and activating this gene was marketed as one of the most reliable ways of increasing lifespan. Resveratrol was lauded as one of the most … Read more SIRT1 is a key promoter of leukemia and other blood cancers