Elevated serotonin may cause schizophrenia and bipolar disorder

The study and even the popular press article are fairly technical so I won’t go into the full details here but I will just give a TLDR. Namely, the study below provides strong evidence that lower levels / expression / activity of the serotonin transporter (SERT) protein is likely a direct cause of schizophrenia, bipolar … Read more Elevated serotonin may cause schizophrenia and bipolar disorder

PUFA and serotonin promote each other, and likely cause mental illness

I neat new study that draws a direct parallel between PUFA-driven inflammation, serotonin and depression. As the study demonstrated, high levels of the PUFA arachidonic acid (AA) are highly correlated with lower density (expression) of the serotonin transported (SERT, 5-HTT), and the relationship is actually causative in both directions (AA<->serotonin). This results in increased serotonin … Read more PUFA and serotonin promote each other, and likely cause mental illness

Serotonin excess, not dopamine deficiency, may be the cause of Parkinson

One of the most paradigm-challenging studies I have seen this year and, unsurprisingly, mainstream media is pulling all sorts of tricks to avoid naming the culprit directly. Even the press release and the study abstract are worded in a convoluted way, talking about a “serotonin dysfunction” instead of what the results of the study demonstrated … Read more Serotonin excess, not dopamine deficiency, may be the cause of Parkinson

Elevated serotonin increases criminal activity

The study looked at correlations between ambient temperature and criminal activity and found that higher temperatures correlate with reduced SERT density and as such elevated extracellular serotonin. The SERT protein is the one that deactivates serotonin and it is a sodium-dependent protein. https://en.wikipedia.org/wiki/Serotonin_transporter Unfortunately, the popular press article that picked up this study included their … Read more Elevated serotonin increases criminal activity