Serotonin (5-HT) is a key driver of asthma

Yet another blow to the status of the so-called “happiness hormone”. While histamine, acetylcholine, and estrogen have long been known as key drivers of asthma the link between the mast cells and the nervous system’s production of the vasoconstrictor acetylcholine has remained unknown. The study below demonstrates that the release of serotonin (5-HT) from mast … Read more

Serotonin may be the “aggression hormone” in most living organisms

So much for the “happiness hormone”, which medicine keeps telling us should be kept as high as possible. This idiotic hypothesis gave birth to an entire drug industry, which continues to poison people to this day with its SSRI drugs, despite solid evidence that they are no better than placebo, do not reduce depressive symptoms, … Read more

Serotonin promotes (futile) patience and (false) faith in future rewards

This study alone explains so much of the pathological behavior seen in humans living in developed countries. Namely, the vast majority of them are willing to break their backs working and “delaying gratification” in the hopes that one day they will “make it” and all of their efforts will be generously rewarded. Of course, this … Read more

Serotonin (and SSRI drugs) can cause anxiety and PTSD

Yet another great study exposing just how much of a “happy hormone” serotonin really is. As usual, the popular press article does everything possible to avoid pointing the finger at serotonin and even engages in misdirection. For example, it says that SERT is the main target of drugs like cocaine, while in reality it is … Read more

Serotonin may cause schizophrenia, Parkinson, and Alzheimer diseases

One by one, medical myths (slowly) go the way of the Dodo. Two of the most pervasive such myths are that psychotic conditions like schizophrenia are caused by excess dopamine, and Parkinson Disease (PD) is caused by a deficiency of dopamine. Unbeknownst even to most doctors, studies exist demonstrating that hallucinations (indistinguishable from those in … Read more

Irritable bowel syndrome (IBS) caused by histamine and serotonin

I did not expect to see this statement in a mainstream science news outlet, but here it is below. I am starting to see a change in attitude towards serotonin but mainstream medicine is careful about its game. Somehow, the message about serotonin has now split into two separate, nonsensical ones – i.e. there are … Read more

Activation of the endotoxin receptor (TLR4) may cause hearing loss

There is currently an epidemic of tinnitus (ear ringing) and hearing loss in virtually all developed countries. Experts are scratching heads and are failing to come up with a reason/explanation for this epidemic. As it often happens, the cause is often hidden in plain sight and if one follows the clues and the available evidence, … Read more

Parkinson Disease (PD) may begin in the gut

The article below is one of at least 20 I have seen in just 2020 alone that are starting to draw attention to the metabolic/inflammatory origins of yet another neurological disease of “mysterious” origin – namely, Parkinson Disease (PD). What makes this article both interesting and infuriating is that apparently the connection between gut pathology, … Read more

Prenatal stress ups serotonin, which causes autism and mental disease in offspring

Another good study, which not only corroborates the causative role of elevated serotonin in a number of behavioral disorders in children (which extend into adulthood) but demonstrates the key role of endotoxin (LPS) in that process. Namely, the pregnant animals exposed to stress who had sterile guts were immune to the pro-inflammatory effects of stress … Read more

Elevated serotonin may cause schizophrenia and bipolar disorder

The study and even the popular press article are fairly technical so I won’t go into the full details here but I will just give a TLDR. Namely, the study below provides strong evidence that lower levels / expression / activity of the serotonin transporter (SERT) protein is likely a direct cause of schizophrenia, bipolar … Read more