Progesterone and allpregnanolone are protective against COVID-19

I think we will be seeing more studies on this topic, especially in light of the ongoing human studies administering progesterone or (gasp!) estrogen to men in the hopes of improving the course of their COVID-19 disease. The results from the estrogen trials are already – surprise, surprise – strongly negative, and the progesterone trials … Read more

The tetracyclines protect against sepsis independently of their antibiotics effects

A remarkable study, which demonstrates that not all antibiotics have been created equal. Namely, the tetracycline family of antibiotics is strikingly protective against lethality from sepsis, and that protection is completely separate from their antibiotics effects. For example, the study demonstrated that pre-treatment with a puny single dose of doxycycline in a HED of 0.25 … Read more

Inhibiting fatty acid synthesis (FAS) dramatically improves sepsis survival rate

Yet another study that points the finger straight at fat as a key factor in one of the most common causes of inpatient hospital mortality – sepsis. Sepsis is currently considered to be a condition of infectious (bacterial) etiology, driven by endotoxin. However, in light of the new findings it may be more appropriate to … Read more