Tag: ROS
Increased fat oxidation (FAO) sufficient to cause senescence/aging/disease
A very interesting study, and one of the few that I have seen openly acknowledge the existence…
Lactate damages mitochondria and can cause (pulmonary) fibrosis
In the first half of the 20th century lactate had a largely negative reputation in medical circles…
Stress/Injury (mitochondrial dysfunction) sufficient to cause de-differentiation, even cancer
One of the most pernicious myths in medicine is the “irreversibility” of several cellular processes related to…
Mitochondrial dysfunction is a major cause of cardiovascular disease (CVD)
At a first glance, mitochondrial dysfunction (a “functional” problem) has little in common with the build-up of…
Blocking PUFA metabolism may treat Amyotrophic Lateral Sclerosis (ALS)
The disease ALS needs no introduction. It is perhaps the most dreaded disease in current/former athletes as…
Diabetes, Alzheimer’s, cancer are bioenergetic diseases; PUFA may be the cause
The bad news for PUFA (in this case linoleic acid) just keep piling on. At this point,…
Reductive stress drives pathogenesis and progression of tuberculosis
I am posting this study b/c it is one of the few I have seen lately demonstrating…
Uncoupling metabolism/OXPHOS may treat inflammatory conditions
In several of his articles and interviews, Peat mentioned that one of the reliable signs/symptoms of low…
How lipolysis may damage organs such as the heart
It is well-known in endocrinology, and especially among doctors specializing in diabetes, that excessive lipolysis is highly…
Metabolic (energy) deficiency may be the cause of Parkinson Disease (PD)
The dogma that PD is just a simple dopamine deficiency manifesting in genetically vulnerable individuals is quickly…