To Extract Knowledge from Matter
Perceive, Think, Act
Just a quick post in regards to a study that found the drug donepezil – commonly used to “treat” Alzheimer’s Disease (AD) – may improve mitochondrial function in muscles. While the findings of the study in regards to donepezil are debatable and not particularly interesting, buried inside the actual study is the finding that AD … Read more
The evidence for the fat-loving nature of cancer just keeps on accumulating. During the last podcast with Danny and Ray, I mentioned that in cancer cells the enzyme fatty acid synthase (FAS) is actually part of the estrogen receptor (ER) complex. As such, anything that increases the expression/activity of one promotes the other as well. … Read more
Just a quick post on a study that provides insight as to how increased fatty acid oxidation (FAO) can “paradoxically” result in increased FAS as well, thus leading to a vicious cycle most commonly seen in diabetes and cancer. One of my recent posts discussed a much more recent study that demonstrated the same effect … Read more
The evidence continues to pile on that naming the (in)famous observation made by Otto Warburg in regards to cancer an “effect” is one of the most profound falsehoods the medical profession has ever concocted. Almost a century after the Warburg “Effect” term was coined, the evidence rapidly accumulates that the lactic acidosis is not at … Read more
Yet another study that points the finger straight at fat as a key factor in one of the most common causes of inpatient hospital mortality – sepsis. Sepsis is currently considered to be a condition of infectious (bacterial) etiology, driven by endotoxin. However, in light of the new findings it may be more appropriate to … Read more
Just a few days ago I posted the groundbreaking study on metabolic derangement in ALS – i.e. it is a diseased characterized by increased FAO, which wastes glucose. Simply increasing dietary glucose was able to greatly restrain the pathology. Well, hot on the heels of that study is the study below, which found very similar … Read more
The study below directly contradicts a mantra commonly repeated in nutrition circles – restrict glucose and increase fat oxidation in order to lose weight, and more specifically body fat. In fact, this idea is so ingrained into the minds of most people that I often get hate mail from people all over the world angrily … Read more