Tag: pregnenolone

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Stress/cortisol/aldosterone cause kidney disease; pregnenolone/progesterone treat it

The condition known as chronic kidney disease (CKD) is one of the most common long-term co-morbidity of…

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Progesterone (or pregnenolone) – a cheap, safe and effective treatment of infertility

It looks like Big Pharma is getting desperate and are now setting their sights on progesterone. The…

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Cells preferentially accumulate Pregnenolone (P5), Progesterone (P4), and DHEA

A study not directly dealing with disease, though its findings are probably relevant for all diseases. It…

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Pregnenolone (P5) blocks stress-induced anxiety, hypertension and cocaine cravings

A great new study, and with humans too! As the study aptly demonstrates, the primary driver of…

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Pregnenolone/aspirin can block cellular estrogen uptake, PUFA promotes it

I have posted in the past about the “obscure” estrogen estrone sulfate (E1S) and its role as…

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Pregnenolone (P5) improves recovery from stroke

One of the few direct studies with P5 in-vivo, though that may be changing as I noticed…

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Stress causes/exacerbates allergies, pregnenolone/progesterone therapeutic

Yet another studies demonstrating the “controversial” link between stress and a condition doctors insist has nothing to…

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Oral pregnenolone as hormone replacement therapy (HRT) in humans

As many of my readers know, the first step in steroid synthesis is the so-called “side-chain cleavage”,…

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Topical DHEA has potent anti-aging effects on human skin

I often get emails in regards to possible interventions with anti-aging effects on skin. The study I…

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Pregnenolone (P5) may be ergogenic and helps recovery from exercise

Take this study with a grain of salt simply because the only link to it is from…