Inhibiting respiration/metabolism reliably causes bipolar disorder

Just a quick post on a study, which claims to have established a reliable method for inducing bipolar disorder in an animal model. This reliable method consists simply of administering a low-dose of a mitochondrial inhibitor. More specifically, an inhibitor of complex I of the electron transport chain (ETC). The chronic, low-dose administration reliably reproduced … Read more

Reduced pyruvate and/or increased lactate drive heart failure

I just did a post on the role of reduced glucose metabolism, lower pyruvate/NAM/NAD and elevated lactate in the pathogenesis of glaucoma. Just minutes later, another study popped up in my newsfeed. Namely, a study that demonstrates the exact same metabolic disturbances as the main drivers of heart failure. The study below demonstrates that heart … Read more

Glaucoma likely a metabolic disease, treatable by pyruvate and/or niacinamide

About a year ago, a publication came out that demonstrated therapeutic effects of raising the (mitochondrial) NAD/NADH ratio in glaucoma patients. That study used niacinamide (NAM) and suggested that the “irreversible” changes in eye structure seen in glaucoma patients are in fact nothing more than a downstream effect of metabolic (OXPHOS) disturbances. Now, a new … Read more

Niacinamide may treat ALS by improving energetic state

Another study sent to me by the Austrian collaborator. Once again, the energetic origin of “incurable” diseases like amyotrophic lateral sclerosis (ALS) is on full display. The study elucidates that ALL types of ALS are characterized by metabolic/energetic abnormalities and the metabolic phenotype of that disease is indistinguishable from cancer. In other words, little to … Read more

Low, not high, metabolism creates oxidative stress

A hugely popular tenet of the “rate of living” theory is that the higher the metabolic rate the more reactive oxygen species (ROS) an organism produces. ROS elevation has already been implicated in a host of chronic disease including diabetes, CVD, cancer, neurological conditions and even mental health disorders. However, the explanation of higher ROS … Read more

Low metabolism, cellular debris may cause Huntington Disease (HD)

Yet another study demonstrating the crucial role of oxidative metabolism (OXPHOS) in a chronic degenerative condition considered largely genetic in origin. Just as importantly, the study corroborates findings from other recent reports/experiments demonstrating that the presence of cellular debris in the blood stream is anything but benign. The presence of such debris is interpreted by … Read more

Exposure to fluoride actually damages teeth, even at low concentrations

Most adults are familiar with the much-publicized (and advertised) claims of public health authorities about the purported benefits of fluoride exposure for dental health. The official story is that by adding fluoride to tap water, people’s teeth are exposed to “low” concentration of fluoride, which has a strengthening effect on the enamel and makes it … Read more

Simple heating of tumor often leads to a rapid and complete cure

As many readers of my blog know, one of the primary signs/symptoms in cancer patients is the frequent occurrence of fevers. The official position of mainstream medicine is that the cause of these fevers is unknown but may have to do with the so-called “tumor lysis syndrome“. Regardless, the fever is considered something peripheral to … Read more

Low Dose Lithium May Stop Alzheimer’s Disease (AD) in Its Tracks

This study was sent to me by one of my Twitter followers. In some of my past interviews/podcasts, I did mention isolated published case studies, as well as anecdotal medical reports of even advanced cases of AD getting rapidly reversed by micro-dosing regimens using lithium salts such as aspartate or orotate. The doses reported by … Read more

Metabolic dysfunction is a primary cause of aging and its symptom Alzheimer Disease (AD)

As it seems, not all hope is lost when it comes to mainstream medicine. Just a few days ago I posted about a landmark human study with AD demonstrating that the a low daily dose of the cheap, unpatentable chemical methylene blue (MB) may stop AD. LSD may do the same, and both MB and … Read more