Glucocorticoids may increase inflammation in the long run

Glucocorticoids (both bioidentical and synthetic) are some of the most widely used drugs in the clinical setting, as well as in outpatient treatment for all sorts of ailments – i.e. autoimmune conditions, joint pain, post-operative inflammation, asthma, and even infectious diseases such as COVID-19. The officially improved indications for those glucocorticoid drugs continue to increase … Read more

PUFA promote torpor / hibernation, decrease lifespan

Not many studies on this topic, but here is one that will hopefully satisfy my critics who keep complaining that there is no evidence for the anti-metabolic, pro-hibernation effects of PUFA. Apparently, PUFA is sought after by hibernating animals (but even they consume it within very tightly controlled amounts/seasons) and universally avoided by non-hibernating ones … Read more

PUFA are potent immunosuppresive agents

Just a quick post for all those PUFA/fish-oil lovers who keep sending me hate-mail about the “incredibly beneficial” omega-3, and even omega-6 (e.g. some athletes/bodybuilders tout arachidonic acid as a natural “anabolic agent”). As the study below discusses, all PUFA, but especially omega-3, are about as potent as glucocorticoids in inducing T-cell death. Modern medicine … Read more

Alzheimer Disease (AD) linked to PUFA accumulation in brain

So much for the “beneficial” effects of PUFA. What makes this study particularly interesting is that it calls into question a favorite defensive maneuver of clinical nutritionists. Namely, when challenged about the known inflammatory effects of omega-6 fatty acids, most medical professionals make a desperate claim that omega-3 fatty acids are actually protective and we … Read more

PUFA may be a major factor in sterility

Just a few days ago I made a post about PUFA driving obesity, inflammation, and liver damage in diabetes II patients. The omega-6 fatty acid DLGA (a metabolite of linoleic acid) was the main pathological factor examined in that study. Now, a new study study demonstrates that DLGA may also cause sterility. Official estimates indicate … Read more

PUFA increases risk of all cancers, especially prostate

The bad news for PUFA just keep on coming. There seems to be no health pathology that PUFA does not promote, even indirectly. The study below demonstrates that BOTH omega-3 and omega-6 increase risk of ANY cancer and death from it, but specifically the risk of aggressive prostate cancer. It is mind boggling that in … Read more

Diet (PUFA) causes inflammatory bowel disease (IBD)

Rates of inflammatory bowel diseases (IBD) such as ulcerative colitis (UC) have been steadily increasing and predominantly so in the youngest cohorts studied. The official cause of UC is of course “unknown” even though the public health authorities do admit that an environmental agent is most likely at fault. UC is an “autoimmune” condition and … Read more

PUFA is a cancer “sensitizer”

A neat study, which demonstrates that in addition to its direct carcinogenic effects, PUFA is also a cancer “sensitizer” – i.e. is triggers the development of cancer in the presence of less-than-healthy chemicals that are relatively harmless by themselves. This sensitizing role of PUFA seems to be well-known to the research community and applies to … Read more

PUFA may drive obesity, insulin resistance, liver issues in diabetes II patients

Yet another study where the message is clear – there is nothing “essential” about the PUFA we are bombarded with from all directions be that diet, medical interventions, household products, etc. What makes this study particularly relevant is that PUFA ingestion actually is promoted as one of the healthiest ways to keep weight at bay, … Read more