mitochondria

Increasing metabolism may reverse Alzheimer Disease (AD) and general aging

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Yet another study demonstrating the remarkable parallels between the decline in function (metabolism) and the structural abnormalities that occur not only in specific pathologies such as AD but also in the generalized degradation known as “aging”. FDA currently does not recognize aging as a disease, but the evidence for it is rapidly accumulating. Just a … Read more Increasing metabolism may reverse Alzheimer Disease (AD) and general aging

Progesterone may treat diabetes, obesity, and metabolic syndrome

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Interesting new study, which adds more to the already existing mountain of evidence for the benefit of progesterone in a variety of conditions of metabolic origin. While the study does not mention any specific doses, it is known that the receptor (PGRMC2) whose activation the study found to be beneficial for diabetes/obesity, is activated by … Read more Progesterone may treat diabetes, obesity, and metabolic syndrome

Aging likely caused by decreased respiration / metabolism, not genetic mutations

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It looks like after a century of utter idiotism in biology and medicine, those two disciplines may finally be getting on the right course. Despite the fact that the “rate of living” theory is still the dominant theory of aging in the halls of academia, a new generation of scientists is emerging that is not … Read more Aging likely caused by decreased respiration / metabolism, not genetic mutations

Blue light accelerates aging and reduces lifespan by more than 50%

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In one of his interviews, Peat mentioned that red light exposure may be the most fundamental protective factor in nature, and that a deficiency of it (as commonly seen in Western lifestyles) may be the main driver of systemic aging and the diseases associated with it. The study below provides strong evidence in support of … Read more Blue light accelerates aging and reduces lifespan by more than 50%

Energy deficiency due to stress causes anxiety, panic disorders, and subbordination

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This is a great study on so many levels. First, it directly demonstrates that chronic stress leads to mitochondrial dysfunction and reduced oxidative phosphorylation. Second, it demonstrates that glucocorticoids (cortisol) are a direct cause of this energy production downregulation. Third, it demonstrates a direct parallel between animal models and human mood/mental disorders by comparing the … Read more Energy deficiency due to stress causes anxiety, panic disorders, and subbordination

Mitochondrial damage and fatty acid buildup, not elevated glucose, may drive diabetes

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Finally some common sense is coming out of mainstream medicine. The study below demonstrates that it is the buildup of fatty acid metabolites and mitochondrial damage that drives the chronic inflammation now known to be a major causative factor for diabetes II (T2DM). Aside from corroborating the role of fat in diabetes, as well as … Read more Mitochondrial damage and fatty acid buildup, not elevated glucose, may drive diabetes

MS Tied To Glucose Deficiency Due To Endotoxin And Fat, Extra Glucose May Treat It

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Just a few days ago I posted the groundbreaking study on metabolic derangement in ALS – i.e. it is a diseased characterized by increased FAO, which wastes glucose. Simply increasing dietary glucose was able to greatly restrain the pathology. Well, hot on the heels of that study is the study below, which found very similar … Read more MS Tied To Glucose Deficiency Due To Endotoxin And Fat, Extra Glucose May Treat It

Osteoporosis is caused by mitochondrial dysfunction, driven by nitric oxide (NO)

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Let’s repeat the mantra one more time – structure and function cannot be separated, they are interdependent at every level of reality/life. As such, it is little surprise (to us) that a structural disorder like osteoporosis may be caused by a deficiency in energy production. Yet, despite being a sacrilege to utter this in a … Read more Osteoporosis is caused by mitochondrial dysfunction, driven by nitric oxide (NO)

Mitochondria (energy) as the main driver of health, intelligence, and aging

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We are finally starting to see Peat enter the mainstream and article like the one below are calling for a complete review of what we know about health and aging and how intelligence is tied to them. As the authors says, or actually borrows from Peat, there is solid evidence that mitochondrial function and ATP … Read more Mitochondria (energy) as the main driver of health, intelligence, and aging

Damaged mitochondria and endotoxin (LPS) drive chronic inflammation

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Chronic, low-grade inflammation has now been recognized as the main cause behind a number of chronic degenerative conditions including CVD, diabetes, cancer, Alzheimer, Parkinson, etc. Mainstream medicine claims that the cause of this chronic low-grade inflammatory reaction is unknown, despite the well-known role PUFA play as precursors of the most important inflammatory mediators (prostaglandins and … Read more Damaged mitochondria and endotoxin (LPS) drive chronic inflammation