In a recent post of mine I discussed the effects of cortisol on various aminotransferases (especially TAT), their role as biomarkers of catabolism, and how inhibitors of said aminotransferases have a potent anti-catabolic / anabolic effects. In that same post, I also described how cortisol (a catabolic steroid) is, naturally, a potent inducer of those … Read more Vitamin D is anti-catabolic / anabolic, protects liver from cortisol injury
A neat little study, which demonstrates once again the crucial role of energy and optimal redox status in a public health issue that has now reached catastrophic proportions. Namely, alcohol-related morbidity and mortality. Those have always been an issue in any developed country but since the start of the “pandemic” have exacerbated dramatically. As most … Read more Alcohol causes liver (and other organ) damage by lowering NAD/NADH ratio
As many of my readers know, currently there is an epidemic of the condition known as non-alcoholic fatty liver disease (NAFLD). By some estimates, more than 30% (100mil) of people living in the US have NAFLD and in about 25% of those the condition will progress to the more severe form known as non-alcoholic steatohepatitis … Read more Vitamin E can treat/cure severe fatty liver disease (NASH) in humans
A number of my blog readers contacted me over the last 2 weeks and urged me to write this post in response to the recent FDA approval of the first oral testosterone (T) product in the USA. The approved product will contain the testosterone ester undecanoate in the form of tablets. https://www.fda.gov/news-events/press-announcements/fda-approves-new-oral-testosterone-capsule-treatment-men-certain-forms-hypogonadism Well here is my … Read more Oral free/base (unesterified) testosterone is more effective and safer than synthetic AAS
As many of my readers already know, there are a number of human studies, going back to at least the 1960s, demonstrating that supplementation with saturated fats (SFA) protects the liver from damage induced by alcohol. I fact, supplementation with SFA not only prevents alcohol-induced liver damage but actually fully reverses the fibrosis/cirrhosis induced by … Read more Supplementation with (long chain) saturated fats protects liver from alcohol
Another great study about aspirin. What I particularly like about this study is that one of the authors is calling aspirin “a promising anti-fibrotic strategy for NAFLD”. This is the first time I have heard a doctor refer to aspirin as anti-fibrotic chemical. Peat mentioned aspirin as one of the most protective chemicals for liver … Read more Daily aspirin reduces by 37% risk of fatty liver progressing into cirrhosis
As Peat has written many times, there is truly no such thing as “beneficial” gut bacteria as long as they are capable of producing endotoxin (LPS). And since most bacterial species known to colonize the gut can produce LPS when exposed to undigested food or mechanical stimulation (stretching or even bouncing the intestine through, say, … Read more All gut bacteria is dangerous, their endotoxin drives liver cancer; antibiotics can cure.
Yet another sad reminder of just how much the health of the average person has declined over the last 20 years. If these trends are not reversed or at least slowed down, we may start seeing people in their 20s filing for Medicare/Medicaid due to rapidly declining health and inability to cover their health expenses … Read more Epidemic of NAFLD and NASH in young people