Oral testosterone + vitamin E may treat NAFLD, NASH, cirrhosis in humans

Several years ago, I posted a few studies from the 1970s demonstrating very high cure rates of advanced cirrhosis in humans with a combination treatment of testosterone (T) and vitamin B1 (thiamine). Not bad for a condition modern medicine tells us is incurable and the only option the patient has is a liver transplant. https://pubmed.ncbi.nlm.nih.gov/14139786/ … Read more

Glycine (and leucine) can treat fatty liver (NAFLD and NASH)

A great new study that demonstrates the strong protective effects of glycine, alone or in combination with leucine, on preventing/treating various forms of fatty liver disease, as well as the obesity that often accompanies these conditions. One of the strong points of the study is that it also established a minimum daily dosage needed to … Read more

Vitamin D is anti-catabolic / anabolic, protects liver from cortisol injury

In a recent post of mine I discussed the effects of cortisol on various aminotransferases (especially TAT), their role as biomarkers of catabolism, and how inhibitors of said aminotransferases have a potent anti-catabolic / anabolic effects. In that same post, I also described how cortisol (a catabolic steroid) is, naturally, a potent inducer of those … Read more

Alcohol causes liver (and other organ) damage by lowering NAD/NADH ratio

A neat little study, which demonstrates once again the crucial role of energy and optimal redox status in a public health issue that has now reached catastrophic proportions. Namely, alcohol-related morbidity and mortality. Those have always been an issue in any developed country but since the start of the “pandemic” have exacerbated dramatically. As most … Read more

Vitamin E can treat/cure severe fatty liver disease (NASH) in humans

As many of my readers know, currently there is an epidemic of the condition known as non-alcoholic fatty liver disease (NAFLD). By some estimates, more than 30% (100mil) of people living in the US have NAFLD and in about 25% of those the condition will progress to the more severe form known as non-alcoholic steatohepatitis … Read more

Oral free/base (unesterified) testosterone is more effective and safer than synthetic AAS

A number of my blog readers contacted me over the last 2 weeks and urged me to write this post in response to the recent FDA approval of the first oral testosterone (T) product in the USA. The approved product will contain the testosterone ester undecanoateĀ in the form of tablets. https://www.fda.gov/news-events/press-announcements/fda-approves-new-oral-testosterone-capsule-treatment-men-certain-forms-hypogonadism Well here is my … Read more

Supplementation with (long chain) saturated fats protects liver from alcohol

As many of my readers already know, there are a number of human studies, going back to at least the 1960s, demonstrating that supplementation with saturated fats (SFA) protects the liver from damage induced by alcohol. I fact, supplementation with SFA not only prevents alcohol-induced liver damage but actually fully reverses the fibrosis/cirrhosis induced by … Read more

Daily aspirin reduces by 37% risk of fatty liver progressing into cirrhosis

Another great study about aspirin. What I particularly like about this study is that one of the authors is calling aspirin “a promising anti-fibrotic strategy for NAFLD”. This is the first time I have heard a doctor refer to aspirin as anti-fibrotic chemical. Peat mentioned aspirin as one of the most protective chemicals for liver … Read more

All gut bacteria is dangerous, their endotoxin drives liver cancer; antibiotics can cure.

As Peat has written many times, there is truly no such thing as “beneficial” gut bacteria as long as they are capable of producing endotoxin (LPS). And since most bacterial species known to colonize the gut can produce LPS when exposed to undigested food or mechanical stimulation (stretching or even bouncing the intestine through, say, … Read more