To Extract Knowledge from Matter
Perceive, Think, Act
A great study, demonstrating that in diabetes (just as in cancer) the so-called Warburg Effect (aerobic glycolysis) is as much a cause of those degenerative conditions as it is an effect of. The study below demonstrated that increased intracellular lactate results in robust increase in systemic release of inflammatory cytokines, resulting in aggravation of systemic … Read more
A great human study on the beneficial effects of androgens for a variety of metabolic biomarkers associated with insulin resistance and diabetes II. The only gripe I have with this study is that they claim it was conducted with “healthy” men when in reality all men had low plasma total testosterone (PTT), which of course … Read more
A great study, which both highlights the dangers of statins while also providing a plausible mechanism for those side effects that both FDA and Big Pharma vehemently continue to dispute. This plausible mechanism involves the inhibition of vitamin K2 (MK-4) synthesis, which requires the same enzymes that synthesize cholesterol. As the authors themselves state, vitamin … Read more
Yet another study where the message is clear – there is nothing “essential” about the PUFA we are bombarded with from all directions be that diet, medical interventions, household products, etc. What makes this study particularly relevant is that PUFA ingestion actually is promoted as one of the healthiest ways to keep weight at bay, … Read more
A neat study, albeit lasting much longer (about 1.5 years) than most other intervention studied with vitamin D. What makes this study particularly interesting is that it only used high doses vitamin D (60,000 IU once weekly) initially until blood levels rose into the normal range. It did not seek to achieve a specific target … Read more
Despite the ongoing assault against “ineffective” dietary supplements, the evidence in favor of them keeps piling on. One of the favorite targets of mainstream media is vitamin D, and multiple claims of “ineffectiveness” based on “meta” studies have come out in the last 5 years. Usually, this is a sign that something big, and financially … Read more
I really hope the keto community and other low-carb diet afficionados are taking note of the stream of recent studies that keep demonstrating a causative link between low-carb and/or high-fat diets, fasting, chronic stress, cortisol and diabetes. The evidence at this point is indisputable, no matter how much effort the medical industry puts into trying … Read more
Over the last year I posted a number of studies demonstrating strong link between serotonin and chronic conditions such as obesity, insulin resistance, and even diabetes. https://www.nature.com/articles/s41366-018-0047-8 https://medicalxpress.com/news/2018-03-obesity-trigger-human-gut.html However, when those studies came out the medical authorities immediately countered with the argument that it is not serotonin that is the culprit but changes in the … Read more
Just a few days ago I posted the groundbreaking study on metabolic derangement in ALS – i.e. it is a diseased characterized by increased FAO, which wastes glucose. Simply increasing dietary glucose was able to greatly restrain the pathology. Well, hot on the heels of that study is the study below, which found very similar … Read more
As many readers know, there is an epidemic of vitamin D deficiency. It is of worldwide proportions, but is visible mainly in “developed” countries in the Western world. The official stance of mainstream medicine is that while vitamin D deficiency is undesirable, it does not really have much clinical relevance except for older people at … Read more