SHBG may be a good test for liver (metabolic) health

A very good study, which probably runs counter to the “mantra” most bodybuilders adhere to – i.e. they would say one must keep their SHBG low in order to increase levels of “free” steroids since, the claim goes, only free steroids are active and capable of influencing cells. If SHBG is high, the claim is … Read more

The “burning mouth” syndrome may be due to vitamin deficiencies, hypothyroidism

Just a quick post since I get a lot of emails about this issue, and apparently the rates have increased a lot since the pandemic began. According to the study below, this symptoms can be caused by insulin resistance, vitamin D/B6/B1 or zinc deficiencies, or hypothyroidism (high TSH). Looking at those issues, one immediately sees … Read more

DHT can stop aging of the pancreatic beta-cells (insulin-producing)

Another great study, which demonstrates that far from being a “villain” (in both males and females) DHT is in fact a crucial and positive factor in health. In this specific study below, it was demonstrated that DHT dose-dependently inhibited the aging/dysfunction of the pancreatic beta-cells, and the highest dose of DHT tested completely stopped that … Read more

DHEA causes fat-loss and improved glucose metabolism in humans

Another study corroborating the role of DHEA as one of the “youth” hormones. A recent study already demonstrated that DHEA can reverse aging of the human immune system, which usually goes hand in hand with lower cortisol and improved metabolism. The proven anti-cortisol effects of DHEA are probably the reason behind its effects on decreasing … Read more

Replacing starch with sucrose increases metabolism, prevent obesity

A study that will certainly generate controversy in the low-carb blogosphere, but the findings are hard to dispute. Namely, feeding a diet for 15 weeks, in which 74.3% of the calories come from carbs in the form of starch was clearly obesogenic, caused insulin resistance and elevated blood glucose, triglycerides, and free fatty acids (FFA). … Read more

DHT better (and safer) than testosterone for improving blood pressure, insulin levels

A great human study on the beneficial effects of androgens for a variety of metabolic biomarkers associated with insulin resistance and diabetes II. The only gripe I have with this study is that they claim it was conducted with “healthy” men when in reality all men had low plasma total testosterone (PTT), which of course … Read more

Blocking endotoxin (LPS) may reverse/cure diabetes type I (insulin dependent)

Yet another study demonstrating the key role of endotoxin in the pathology of perhaps the most widespread chronic disease – diabetes. The study below discovered that the proliferation of the insulin-producing beta-cells in the pancreas is controlled almost entirely by the TLR4/TLR2 receptor family. Activation of those receptors led to rapid death of beta-cells and, … Read more