inhibitor

Inhibiting fatty acid synthesis (FAS) dramatically improves sepsis survival rate

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Yet another study that points the finger straight at fat as a key factor in one of the most common causes of inpatient hospital mortality – sepsis. Sepsis is currently considered to be a condition of infectious (bacterial) etiology, driven by endotoxin. However, in light of the new findings it may be more appropriate to … Read more

Niacinamide, tetracyclines may prevent / reverse vascular calcification

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The study below demonstrates that vascular (and other soft tissue) calficiation depends on overpexression of the enzyme Poly (ADP-ribose) polymerase (PARP). Inhibiting the synthesis/activity of that enzyme prevented vascular calficiation, and as such can be a powerful prevention tool for CVD and in general any ischemic event. The study used minocycline (a tetracycline-family antibiotic) as … Read more