Androgens boost, estrogen inhibits, anti-aging gene Klotho

This post has two main messages, based on the studies below. Namely, androgens (and especially DHT) potently increase the expression of the anti-aging gene Klotho while estrogens strikingly decrease its expression. Moreover, the more potent the androgen, in terms of androgen receptor (AR) agonism, the more robustly it increases Klotho. Conversely, the most potent the … Read more Androgens boost, estrogen inhibits, anti-aging gene Klotho