Heart attack survivors have high stress (cortisol/adrenaline) hypersensitivity, low androgens

A very interesting study that highlights yet again the connection between chronic stress and ill systemic health, especially cardiovascular disease (CVD). The study demonstrates that people who had experienced a heart attack have dramatically higher higher cortisol and adrenaline/noradrenaline levels, combined with low levels of androgens such as testosterone and DHEA a full 6 months … Read more Heart attack survivors have high stress (cortisol/adrenaline) hypersensitivity, low androgens

Sexual activity and stress levels (HPA activity) may determine longevity

The study below tried to tease out the main factors affecting the longevity of the legendary naked mole rat – the animal with longest lifespan in its genus, and the sole mammal known to be virtually immune to developing cancer. Most of the biological/biochemical findings in regards to naked mole rats have already been found … Read more Sexual activity and stress levels (HPA activity) may determine longevity

Blocking cortisol may treat even terminal cancers

The metabolic causes of cancer are slowly starting to be recognized, and especially the role of cortisol. I recently did a post on the role of cortisol in triple-negative breast cancer and the protective effects of androgens such as DHT. Now, mainstream medicine does not deny that androgens have therapeutic role in breast cancer (BC) … Read more Blocking cortisol may treat even terminal cancers

Topical DHEA has potent anti-aging effects on human skin

I often get emails in regards to possible interventions with anti-aging effects on skin. The study I usually quote is an old one (circa 1967) that did extensive tests on 200+ people with age range of 57-88 years residing in a retirement home, and demonstrated that topical testosterone (1%) cream had the most potent anti-aging … Read more Topical DHEA has potent anti-aging effects on human skin

DHEA-S completely prevents breast cancer metastasis due to estrogen

A great new study that debunks several myths related to DHEA. One of those myths is that when used in physiological doses DHEA can increase risk of estrogen-positive cancers, especially breast cancer. Another myth is that declining DHEA levels seen with advancing age are simply a consequence of aging and restoring said levels would likely … Read more DHEA-S completely prevents breast cancer metastasis due to estrogen

Estrogen and cortisol, not androgens, suppress immunity

There is a very famous theory in reproductive biology still considered the dominant one in its field. Namely, males have to accept a trade-off between androgen levels and immunity. It is known as the immunocompetence handicap hypothesis (ICHH). Higher androgen levels, the theory goes, allow the male to (physically) outcompete other males around him for … Read more Estrogen and cortisol, not androgens, suppress immunity

Rats can drive cars (to lower stress), befriend robot rats and help them when in trouble

Official/pathological science keeps sternly warning us not to anthropomorphize and to think of animals as nothing but dumb, soul-less automatons. Yet, there has been no evidence discovered in over 100 years of pathological science reign to support such a view. To the contrary, the studies below add even more to the already existing pile of … Read more Rats can drive cars (to lower stress), befriend robot rats and help them when in trouble

Reversing human aging likely possible with progesterone / DHEA

I decided to make a post on this topic after seeing the popular press articles about a study claiming reversal of human biological (as opposed to chronological) aging. That study used human growth hormone (HGH), DHEA and metformin combination as an intervention that restores thymus health and thus reverses immunosenescence (immune system aging). It is … Read more Reversing human aging likely possible with progesterone / DHEA

The (in)famous condition “chemo brain” may be simply a state of low DHEA

The condition known as “chemo brain” is notorious among cancer survivors and many other patients undergoing toxic interventions with chemotherapy and may affect up to 85% of cancer patients. It amounts to severe cognitive dysfunction, memory problems, and even personality changes that result in the patient becoming completely dependent and often unable to care for … Read more The (in)famous condition “chemo brain” may be simply a state of low DHEA