High (extracellular) serotonin causes Alzheimer’s and depression

The utter corruption of “journalism” is once again on full display in MSM. The actual scientific study is very clear in its statements/conclusions that a decrease in the levels of serotonin transporter (5-HTT) led to accumulation of beta-amyloid and onset of depression. Lower levels of 5-HTT – the protein that deactivates serotonin – means higher … Read more

High PTH, low vitamin D implicated in bipolar disorder (BD)

A great study highlighting once again the importance of calcium, vitamin D and especially the pro-inflammatory parathyroid hormone (PTH) for mental health. While there are many studies (both observational and intervention ones) examining the role of vitamin D in mental health, this is one of the very few looking into the role of PTH. It … Read more

Depression fades away when serotonin levels drop

A very, very inconvenient study for mainstream medicine and its Big Pharma goons. The so-called “serotonin hypothesis” is slowly crumbling and the results from the most recent studies are so unequivocal that the fraud about serotonin as the “happiness hormone” may go down in history as one of the most open and grotesque examples of … Read more

Inhibiting respiration/metabolism reliably causes bipolar disorder

Just a quick post on a study, which claims to have established a reliable method for inducing bipolar disorder in an animal model. This reliable method consists simply of administering a low-dose of a mitochondrial inhibitor. More specifically, an inhibitor of complex I of the electron transport chain (ETC). The chronic, low-dose administration reliably reproduced … Read more

Niacinamide may treat depression by improving energetic state

A very interesting study, sent to me by a collaborator who lives in Austria. It demonstrated that depression is accompanied by increased SIRT1 activity (i.e. increased fatty acid oxidation), lower ATP levels and redox balance shifted towards reduction. The study demonstrated that animals without the SIRT1 gene were highly resistant to depression and had high … Read more

Vitamin D prevents cortisol-induced depression and…inflammation

A great study for a number of reasons. First, it discussed openly that in animal research circles cortisol administration is considered an official and reliable method of causing major depression. As the article states, for some reason human medical circles have been unwilling to accept the stress-depression causal link and continue to argue that stress … Read more

Meditation can worsen mental health, even cause clinical psychiatric issues

I have always been ambivalent in regards to meditation, mostly due to its teachings that many perceived problems are simply in “our head” and all we need to do as “treatment” is steer our thoughts in a particular direction. We are flooded with information/advice that once we master whatever technique the specific type of meditation … Read more

The social fabric in Western countries may be unraveling

In one of Peat’s recent newsletters he mentioned that there is an epidemic of mental disease in the population because the evil system these people live is preventing them from living their lives “meaningfully, creatively”. A recent study corroborated Peat’s writings on the truly abysmal state of mental health in young people. Add to that … Read more

Prenatal stress ups serotonin, which causes autism and mental disease in offspring

Another good study, which not only corroborates the causative role of elevated serotonin in a number of behavioral disorders in children (which extend into adulthood) but demonstrates the key role of endotoxin (LPS) in that process. Namely, the pregnant animals exposed to stress who had sterile guts were immune to the pro-inflammatory effects of stress … Read more

A third of Americans show signs of clinical anxiety, depression

The news about deteriorating health of the population just keep piling on. The latest one below shows that at least a third of the US population shows signs of clinical anxiety and/or depression. The reason I put clinical in bold is that it means the pathology is severe enough to require treatment and if left … Read more