Prenatal stress ups serotonin, which causes autism and mental disease in offspring

Another good study, which not only corroborates the causative role of elevated serotonin in a number of behavioral disorders in children (which extend into adulthood) but demonstrates the key role of endotoxin (LPS) in that process. Namely, the pregnant animals exposed to stress who had sterile guts were immune to the pro-inflammatory effects of stress … Read more Prenatal stress ups serotonin, which causes autism and mental disease in offspring

A third of Americans show signs of clinical anxiety, depression

The news about deteriorating health of the population just keep piling on. The latest one below shows that at least a third of the US population shows signs of clinical anxiety and/or depression. The reason I put clinical in bold is that it means the pathology is severe enough to require treatment and if left … Read more A third of Americans show signs of clinical anxiety, depression

Ketamine cures depression by reducing serotonin, increasing dopamine

As many of my readers know, FDA recently approved the party drug ketamine (known as Special-K on the street) as a rapidly-acting antidepressant. The rapid antidepressant effects of ketamine have been known since the 1960s but FDA denied that those effects are relevant in humans and refused to consider “scheduled” illicit drugs for therapeutic uses. … Read more Ketamine cures depression by reducing serotonin, increasing dopamine

SSRI drugs, not depression, destroy empathy

Yet another medical myth gets busted today. A common dogma in psychiatry is that one of the core symptoms of patients with major depressive disorder (MDD) is lack of empathy. In other words, while such patients are perfectly in tune with their own suffering and negative emotions, they are indifferent (and sometimes even pleased) at … Read more SSRI drugs, not depression, destroy empathy

Drop in dopamine behind giving up

I would have much preferred if the authors of the study below investigated the level of serotonin and its relation to giving up (“learned helplessness” anyone?), but I suppose the dogma of serotonin is still too “sacred” to be questioned in biomedical research. So, instead of saying that elevated serotonin causes despair and giving up, … Read more Drop in dopamine behind giving up

The government knows stress causes “learned helplessness” / depression

I have had discussions with numerous psychiatrists about the concept of “learned helplessness” (LH) and its relation to chronic stress. All of those doctors flatly denied that LH is a concept relevant to humans and argued that it is nothing more than a useful model of depression in animal studies, designed to evaluate animal exposure … Read more The government knows stress causes “learned helplessness” / depression

Serotonin causes anhedonia…and mental illness in general

As many of my readers know, anhedonia is one of the most pernicious symptoms of most mental disorders, and is perhaps the most resistant to therapy. It also happens to be one of the main triggers of attempted suicide, based on interviews with suicide survivors. I posted some threads in the past demonstrating that chronic … Read more Serotonin causes anhedonia…and mental illness in general

Chronic stress (adversity) lowers dopamine and causes mental illness

The evidence for the role of chronic stress in virtually every health condition doctors have a name for just keeps on accumulating. Unfortunately, even in this latest study the scientists keep insisting that there is some mysterious and unquantifiable difference between chronic stress “increasing risk of” and “causing” pathology. Yet, those same scientists have no … Read more Chronic stress (adversity) lowers dopamine and causes mental illness

PUFA and serotonin promote each other, and likely cause mental illness

I neat new study that draws a direct parallel between PUFA-driven inflammation, serotonin and depression. As the study demonstrated, high levels of the PUFA arachidonic acid (AA) are highly correlated with lower density (expression) of the serotonin transported (SERT, 5-HTT), and the relationship is actually causative in both directions (AA<->serotonin). This results in increased serotonin … Read more PUFA and serotonin promote each other, and likely cause mental illness

Estrogen is a stress hormone, it can both trigger and potentiate the effects of stress

I was quite surprised to see this article in WebMD – a website that is bastion of mainstream medicine. It regularly promotes dogmas related serotonin, estrogen, oxytocin, growth hormone, etc and the myriad of “benefits” these substances bestow upon humans. However, a bit of truth apparently manages to slip through the censorship every once in … Read more Estrogen is a stress hormone, it can both trigger and potentiate the effects of stress