While estradiol falls, estrone rises with age and is much more relevant for estrogen-driven diseases

I posted a few studies in the past demonstrating that estrone (E1) and especially its long-lasting derivative estrone sulfate (E1S) are reliable biomarkers of both breast and prostate cancer progression/prognosis. However, for some reason the medical industry is obsessed with estradiol and since its levels plummet after menopause this has allowed doctors to declare menopause … Read more

Playfulness, novelty, and leisure are vital for progress and true knowledge

About a year ago I made a post arguing that leisure, desire, playfulness and relaxation are vital for learning and knowledge. The study below now argues that unstructured play similar to the way children play is absolutely vital for making progress in any aspect of life, be that science, technology, politics or even every human … Read more