Progesterone and allpregnanolone are protective against COVID-19

I think we will be seeing more studies on this topic, especially in light of the ongoing human studies administering progesterone or (gasp!) estrogen to men in the hopes of improving the course of their COVID-19 disease. The results from the estrogen trials are already – surprise, surprise – strongly negative, and the progesterone trials … Read more Progesterone and allpregnanolone are protective against COVID-19

Orange juice (OJ) as therapy for all coronaviruses, including SARS-CoV-2

If anybody needs a reason to convince themselves (or their family members) that drinking OJ is beneficial, maybe this new study in the context of COVID-19 will be good enough as evidence. It demonstrated that one of the main components of OJ – naringenin – is a powerful inhibitor of viral replication and it also … Read more Orange juice (OJ) as therapy for all coronaviruses, including SARS-CoV-2

Face masks (at best) ineffective against SARS-CoV-2 / COVID-19 and flu

A series of studies, some of them covering viruses other than SARS-CoV-2, yet the findings of all of them are the same – no statistically significant protective effect of face masks, and, in some cases, possibly increased rates of infection (see first study below). https://www.reuters.com/article/us-health-coronavirus-facemasks-idUSKBN27Y1YW https://www.acpjournals.org/doi/10.7326/M20-6817 “…A total of 3030 participants were randomly assigned to … Read more Face masks (at best) ineffective against SARS-CoV-2 / COVID-19 and flu

Glycine has a universal anti-viral effect

While the study below does not go as far as to say that glycine would be an appropriate intervention for the current COVID-19 pandemic, it does describe an anti-viral mechanism for glycine that is (at least in theory) applicable to ALL viruses. Namely, glycine prevents for formation of capsids, without which viruses are unstable and … Read more Glycine has a universal anti-viral effect

Obesity “paradox” strikes again – protection against COVID-19

I suspect this one will not go down will with the “lean is always good” crowd, which consists predominantly of members of the medical profession. Aside from all the health risks of obesity for pretty much any chronic disease, the news over the last 6 months have been replete with warning from all kinds of … Read more Obesity “paradox” strikes again – protection against COVID-19

Pre-existing COVID-19 immunity in 20%-50% of people – better than vaccines?

A fascinating article that is unfortunately not getting any coverage in mainstream media (MSM). The review is published in BMJ, which is both surprising and also gives it that much more weight. That may be a reason why it is not being covered by MSM – because it argues not only in favor of pre-existing … Read more Pre-existing COVID-19 immunity in 20%-50% of people – better than vaccines?

Policosanol is antiviral and a potent inducer of anti-aging gene Klotho

This post is a good complement to the recent ones I did on androgens, estrogens and their opposing effects on the expression of the anti-aging gene Klotho. While I was doing research on that gene, I had a “random” thought pop up in my mind. It is well-known that some Caribbean countries have a very … Read more Policosanol is antiviral and a potent inducer of anti-aging gene Klotho

PUFA exacerbate, saturated fats (SFA) / albumin / calcium ameliorate COVID-19

A few months ago I posted about a study discussing the role of lipid peroxidation in the COVID-19 pathology. While that study did not make any statements about effects of diet on the disease course/outcome, it did suggest lipid peroxidation blockers such as vitamin E would be therapeutic. Now, we have another study that points … Read more PUFA exacerbate, saturated fats (SFA) / albumin / calcium ameliorate COVID-19

Cytokine storm in COVID-19 / sepsis due to “cancer metabolism” (Warburg Effect)

A few great studies illustrating the crucial effects of metabolism even in “non-metabolic” conditions like COVID-19. We already have evidence that increased PUFA peroxidation is one of the causes behind the (often lethal) cytokine storm in viral diseases, including COVID-19. However, the direct mechanism through which immune cells such as phagocytes “go berserk” and increase … Read more Cytokine storm in COVID-19 / sepsis due to “cancer metabolism” (Warburg Effect)

Magnesium, vitamin D, B12 combo strikingly therapeutic for COVID-19

It is always good to see proof that medicine has not completely lost its mind by blindly chasing only the latest and greatest discovery in pharma antiviral drugs. The preventive and therapeutic effects of magnesium on viral diseases have been known for decades and has prompted the health authorities in several countries to market a … Read more Magnesium, vitamin D, B12 combo strikingly therapeutic for COVID-19