Inhibiting respiration/metabolism reliably causes bipolar disorder

Just a quick post on a study, which claims to have established a reliable method for inducing bipolar disorder in an animal model. This reliable method consists simply of administering a low-dose of a mitochondrial inhibitor. More specifically, an inhibitor of complex I of the electron transport chain (ETC). The chronic, low-dose administration reliably reproduced … Read more

Elevated serotonin may cause schizophrenia and bipolar disorder

The study and even the popular press article are fairly technical so I won’t go into the full details here but I will just give a TLDR. Namely, the study below provides strong evidence that lower levels / expression / activity of the serotonin transporter (SERT) protein is likely a direct cause of schizophrenia, bipolar … Read more