High PTH, low vitamin D implicated in bipolar disorder (BD)

A great study highlighting once again the importance of calcium, vitamin D and especially the pro-inflammatory parathyroid hormone (PTH) for mental health. While there are many studies (both observational and intervention ones) examining the role of vitamin D in mental health, this is one of the very few looking into the role of PTH. It … Read more

PUFA and serotonin promote each other, and likely cause mental illness

I neat new study that draws a direct parallel between PUFA-driven inflammation, serotonin and depression. As the study demonstrated, high levels of the PUFA arachidonic acid (AA) are highly correlated with lower density (expression) of the serotonin transported (SERT, 5-HTT), and the relationship is actually causative in both directions (AA<->serotonin). This results in increased serotonin … Read more