PUFA required for periodontal disease, aspirin may help

It is common knowledge even among mainstream dentists that periodontal disease is caused by bacteria accumulating under the gums, which over time leads to chronic inflammation and thus destruction of both gum tissue and the alveolar/jaw bone underneath the gums. Another “new” discover is that microbiome overgrowth (and thus endotoxin/LPS production) is also involved and … Read more

Aspirin reduces symptom severity, COVID-19 mortality by half

Another great result for aspirin, which I suspect will not see much mainstream media publicity and will probably get censored the moment it hits my Twitter feed:-) Be that as it may, at this point the evidence for available successful/effective treatments for COVID-19 becomes too big to ignore, which of course invalidates the legal rationale … Read more

Air pollution impairs cognition, aspirin is protective

A new study demonstrating that even short-term (less than a month) exposure to polluted air impaired cognition in humans, and that the mechanism of action was by triggering an inflammatory response. Ergo, anti-inflammatory drugs (NSAID) and especially aspirin, were found to be protective. Since the anti-inflammatory effects of aspirin focus mostly on the COX family … Read more

Inflammation (from PUFA), not telomeres, determines lifespan / healthspan

The idea of lifespan being entirely determined by limits on cellular division has ruled biology for more than a century and is perhaps best exemplified by the (in)famous (and false) Hayflick limit. Reaching the said limit is postulated to be controlled by telomere length, and as such the simplistic hypothesis materialized that could extend/control lifespan … Read more

Aspirin beneficial, other NSAID harmful, for COVID-19

Once again, the miracle of nature known as aspirin gets some recognition. Studies done early in the COVID-19 pandemic (early 2020) suggested that non-steroid anti-inflammatory drugs (NSAID) may help reduce severity/lethality of COVID-19, however subsequent studies challenged those results and demonstrated worse outcomes in patients treated with NSAID. As more and more studies were done … Read more

Aspirin may prevent and treat COVID-19

I may get banned from social media for making a post with such a title, but I am simply reporting on what the study discovered. Namely, even a low-dose aspirin used mostly for ischemic attack (heart or brain) prevention reduced risks of SARS-CoV-2 infection by almost 30%, while also shortening the duration of infection by … Read more

DHT / Progesterone / aspirin treat, cortisol ineffective, PUFA promotes prostate cancer

A great study, albeit in-vitro, that once again throws into doubt the entire hypothesis behind prostate cancer. First, it proves the key role of PUFA in the genesis and progression of prostate cancer by demonstrating that inhibitors of the COX enzyme (responsible for synthesizing prostaglandins from PUFA) are therapeutic even when used as a monotherapy. … Read more

Blocking PUFA/prostaglandins restores metabolism and reverses brain aging

The bad news for PUFA has been accumulating for decades, yet public health authorities continue to claim that type of fat is “essential”. Whatever indirect admissions of the pathological role of PUFA in both chronic and acute/infectious diseases is given to the public, is usually confined to the well-known PUFA metabolites known as prostaglandins. However, … Read more

Aspirin has dramatically lower bleeding risk than pharma anticoagulants

Just a quick post that adds to the mountain of evidence contradicting the fearmongering about aspirin we hear on a daily basis from every doctor who manages to get some TV time. It has been known for a while that aspirin lowers bleeding risk in brain and GI tract, despite being an anti-coagulant drug itself. … Read more