To Extract Knowledge from Matter
Perceive, Think, Act
A neat little study, and in-vivo at that, which demonstrates that DHT is a direct estrogen receptor (ER) antagonist. According to the study, so are testosterone, nandrolone and a few other steroids with demonstrated therapeutic effects on ER-positive breast cancer (BC). However, all of the other steroids mentioned by the study are aromatizable and as … Read more DHT is an estrogen (receptor) antagonist
IMO, one of the biggest medical frauds so far is the idea that androgens (especially DHT) cause and promote prostate cancer. We now have an abundance of evidence (posted on this blog) that it is instead deficiency of androgens and/or excess of estrogens that initiates and drives the progression of prostate cancer. When chemical castration … Read more Estrogen may be the cause of “estrogen-negative” breast cancer
It is a “sacred” mantra in the medical and sports worlds – i.e. “estrogen is crucial for males, without it they won’t have any sex life”. This mantra is also part of the justification given for the currently ongoing COVID-19 clinical trials with males receiving estrogen in the hope it will reduce the lethality of … Read more Male sexual function does NOT require estrogen
I just made a post about the role of estrogen in male infertility, which matches perfectly the evidence about estrogen’s role as a metabolic inhibitor, and an agent that causes atrophy in both male and female gonads. Male fertility depends on intensity of (sperm) metabolism Now, a new study demonstrates that using an aromatase inhibitor … Read more Inhibiting estrogen synthesis may treat / prevent ectopic pregnancy
Yet another study demonstrating the causative link between estrogen and a cancer considered to be hormone-independent. Gastric cancer is one of the leading causes of cancer-deaths worldwide, and especially Asian countries. It is considered very hard to treat and most patients are diagnosed at stages when surgery is not a viable option. As such, the … Read more Inhibiting aromatase (to lower estrogen) may treat gastric (stomach) cancer
I decided to make a post on this topic after seeing the popular press articles about a study claiming reversal of human biological (as opposed to chronological) aging. That study used human growth hormone (HGH), DHEA and metformin combination as an intervention that restores thymus health and thus reverses immunosenescence (immune system aging). It is … Read more Reversing human aging likely possible with progesterone / DHEA